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CCL17 / TARC Antikörper (Antigen Affinity Purified)

Produkt-Information von CCL17 / TARC Antikörper

Immunogen

Recombinant Human CCL17 / TARC protein (Catalog#10233-HNAB)

Antibody Type Rabbit Polyclonal Antibody ( Antibody Purification Platform )
Ig Type

Rabbit IgG

Formulation 0.2 μm filtered solution in PBS with 5% trehalose
Preparation

Produced in rabbits immunized with purified, recombinant Human CCL17 / TARC (rh CCL17 / TARC; Catalog#10233-HNAB; Q92583-1; Met 1-Ser 94). CCL17 / TARC specific IgG was purified by Human CCL17 / TARC affinity chromatography.

Usage Guide von CCL17 / TARC Antikörper

Specificity

Human CCL17 / TARC

Western blot This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human CCL17 in WB. Using a DAB detection system, the detection limit for Human CCL17 is approximately 0.5 ng/lane under non-reducing conditions and 1 ng/lane under reducing conditions.
Direct ELISA This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human CCL17. The detection limit for Human CCL17 is approximately 0.00975g/well.
Storage This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Verwandte Produkte & Themen von CCL17 / TARC Antikörper

Related Areas:

Immunology>>Cytokine & Receptor>>Chemokine & Receptor>>CCL17/TARC

Immunology>>>>Monocyte/Macrophage>>Macrophage Marker>>CCL17/TARC

Proteins:
Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
CCL17/TARC Human CCL17/TARC Protein, Recombinant 10233-H08B
CCL17/TARC Human CCL17/TARC Protein, Recombinant, Native 10233-HNAB
CCL17/TARC Mouse CCL17 / TARC Protein, Recombinant 50046-MNAB
Antibodies:
Molecule Application Description //For Detailed Info. and Price------CLICK! Cat. No
Human CCL17/TARC WB, ELISA

CCL17 / TARC Antibody (Antigen Affinity Purified)

10233-RP02
Human CCL17/TARC WB, ELISA

CCL17 / TARC Antibody

10233-MM03

Hintergrund von CCL17 / TARC Antikörper

C-C motif chemokine 17, also known as CC chemokine TARC, Small-inducible cytokine A17, Thymus and activation-regulated chemokine, CCL17 and SCYA17, is a secreted protein which belongs to the intercrine beta (chemokine CC) family. Chemokines are known to regulate the steady-state and inflammatory migration of cutaneous dendritic cells (DCs). The beta-chemokine CCL17, a ligand of CCR4, is inducibly expressed in a subset of DCs and is strongly up-regulated in atopic diseases. CCL17 / SCYA17 is constitutively expressed in the thymus and is produced by dendritic cells (DC), endothelial cells, keratinocytes (KC) and fibroblasts. CCL17 / SCYA17 is expressed at high levels in thymus and at low levels in the lung, colon and small intestine. CCL17 / SCYA17 is a chemotactic factor for T-lymphocytes but not monocytes or granulocytes. It may play a role in T-cell development in thymus and in trafficking and activation of mature T-cells. CCL17 / SCYA17 binds to CCR4.Chemokine receptor CCR4 and its ligands (CCL17 and CCL22) are important for the recruitment of memory T cells into the skin in various cutaneous immune disease.

References

  1. Belperio JA. et al., 2004, J Immunol. 173 (7): 4692-8.
  2. Carpenter KJ. et al., 2005, Infect Immun. 73 (11): 7198-207.
  3. Saeki H. et al., 2006, J Dermatol Sci. 43 (2): 75-84.
  4. Niens M. et al., 2008, Br J Haematol. 140 (5): 527-36.
  5. Stutte S. et al., 2010, Proc Natl Acad Sci. 107 (19): 8736-41.

Sino Biological Inc. liefert CCL17 / TARC Antikörper (Antigen Affinity Purified) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über CCL17 / TARC Antikörper (Antigen Affinity Purified) lesen Sie bitte: http:www.sinobiological.com/CCL17-TARC-Antibody-g-9251.html

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