Pepsinogen C / PGC Antikörper

07.08.2012

Produkt-Information von Pepsinogen C / PGC Antikörper

Immunogen	Recombinant Human Pepsinogen C / PGC protein (Catalog#12072-H08H)
Antibody Type	Rabbit Polyclonal Antibody ( Antibody Purification Platform )
Ig Type	Rabbit IgG
Formulation	0.2 μm filtered solution in PBS with 5% trehalose
Preparation	Produced in rabbits immunized with purified, recombinant Human Pepsinogen C / PGC (rh Pepsinogen C / PGC; Catalog#12072-H08H; NP_002621.1; Met 1-Ala 388). Total IgG was purified by Protein A affinity chromatography.

Usage Guide von Pepsinogen C / PGC Antikörper

Specificity	Human Pepsinogen C / PGC
Western blot	This antibody can be used at 1-2 μg/mL with the appropriate secondary reagents to detect Human PGC in WB.
Direct ELISA	This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect Human PGC . The detection limit for Human PGC is approximately 0.00245 ng/well.
Storage	This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Verwandte Produkte & Themen von Pepsinogen C / PGC Antikörper

Related Areas:

Enzyme>>Protease & Regulator>>Other>>Pepsinogen C/PGC

Proteins:

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
Pepsinogen C/PGC	Human	Pepsinogen C/PGC Protein, Recombinant	12072-H08H
Pepsinogen C/PGC	Rat	PGC / pepsinogen C Protein,Recombinant	80097-R08H

Antibodies:

Molecule	Application	Description //For Detailed Info. and Price------CLICK!	Cat. No
Human Pepsinogen C/PGC	WB, ELISA	Pepsinogen C / PGC Antibody	12072-RP01
Human Pepsinogen C/PGC	WB, ELISA	Pepsinogen C / PGC Antibody (Antigen Affinity Purified)	12072-RP02
Human Pepsinogen C/PGC	WB, ELISA	Pepsinogen C / PGC Antibody	12072-MM07

Hinergrund von Pepsinogen C / PGC Antikörper

Gastricsin, also known as Pepsinogen C and PGC, is a secreted which belongs to thepeptidase A1 family. PGC / Gastricsin hydrolyzes a variety of proteins. PGC / Gastricsin is more restricted specificity than pepsin A, but shows preferential cleavage at Tyr-|-Xaa bonds. It has high activity on hemoglobin. PGC / Gastricsin is an aspartic proteinase that belongs to the peptidase family A1. It is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. It is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Serum levels of this PGC / Gastricsin are used as a biomarker for certain gastric diseases includingHelicobacter pylorirelated gastritis.

References

Moore S.A. et al., 1995, J. Mol. Biol. 247: 466-485.
Khan A.R. et al., 1997, Nat. Struct. Biol. 4: 1010-5.
Roberts,NB. et al., 2003, J Enzyme Inhib Med Chem. 18 (3): 209-17.

Sino Biological Inc. liefert Pepsinogen C / PGC Antikörper mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über Pepsinogen C / PGC Antikörper lesen Sie bitte: http:www.sinobiological.com/Pepsinogen-C-PGC-Antibody-g-9252.html