BPIFA2 / C20orf70 Protein

11.10.2012

Produkt-Information von BPIFA2 / C20orf70 Protein

Synonym	C20orf70 , BPIFA2 ,SPLUNC2
Protein Construction	A DNA sequence encoding the human C20orf70 (Q96DR5)(Met1-Ile249) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
Source	Human
Expression Host	Human Cells

QC Testing von BPIFA2 / C20orf70 Protein

Purity	> 94 % as determined by SDS-PAGE	SDS-PAGE: BPIFA2 protein
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method
Stability	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal	Glu 19
Molecular Mass	The recombinant human C20orf70/Fc is a disulfide-linked homodimer. The reduced monomer comprises 470 amino acids and has a predicted molecular mass of 51.8 kDa. The apparent molecular mass of the protein is approximately 59 kDa in SDS-PAGE under reducing conditions.
Formulation	Lyophilized from a 0.2μm filtered solution of PBS, pH7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.

Usage Guide von BPIFA2 / C20orf70 Protein

Storage	Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution	A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Beschreibung von BPIFA2 / C20orf70 Protein

C20orf70 is a member of the BPI/LBP/Plunc superfamily, Plunc family. PLUNC family is composed of mucosal secretory proteins that are predicted to be structurally similar to lipid-binding and host-defense proteins including bactericidal/permeability-increasing protein and lipopolysaccharide-binding protein. C20orf70 is expected to have molecular function (lipid binding) and to localize in extracellular region. It is a salivary protein of unknown function. C20orf70 can be detected in submandibular gland. C20orf70 gene contains 9 distinct gt-ag introns. Transcription produces 6 different mRNAs, 4 alternatively spliced variants and 2 unspliced forms. There are 2 probable alternative promotors, 3 non overlapping alternative last exons and 4 validated alternative polyadenylation sites. The mRNAs appear to differ by truncation of the 3' end. 80 bp of this gene are antisense to spliced gene glopa, raising the possibility of regulated alternate expression.

References

Lamesch P. et al., 2007, Genomics. 89 (3): 307-15.
Vargas PA. et al., 2008, Oral Dis. 14 (7): 613-9.
Bingle L. et al., 2009, Histochem Cell Biol. 132 (3): 339-49.

Sino Biological Inc. liefert BPIFA2 / C20orf70 Protein mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über BPIFA2 / C20orf70 Protein lesen Sie bitte: http://www.sinobiological.com/BPIFA2-C20orf70-Protein-g-9375.html

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat No
C20orf70	Human	BPIFA2 / C20orf70 Protein, Recombinant	13915-H02H
C20orf70	Human	BPIFA2 / C20orf70 Protein, Recombinant	13915-H08H