APCS / PTX2 / Serum amyloid P component Protein (His Tag)

25.12.2012

Sino Biological Inc. liefert APCS / PTX2 / Serum amyloid P component Protein (His Tag) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über APCS / PTX2 / Serum amyloid P component Protein (His Tag) lesen Sie bitte: http://www.sinobiological.com/APCS-PTX2-Serum-amyloid-P-component-Protein-g-10187.html

Produkt-Information von APCS / PTX2 / Serum amyloid P component Protein

Synonym	APCS, PTX2
Protein Construction	A DNA sequence encoding the human APCS (P02743) (Met1-Val223) was expressed with a polyhistidine tag at the C-terminus.
Source	Human
Expression Host	Human Cells

QC Testing von APCS / PTX2 / Serum amyloid P component Protein

Purity	> 95% as determined by SDS-PAGE	SDS-PAGE: APCS protein
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method
Stability	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal	His 20
Molecular Mass	The recombinant human APCS consists of 215 amino acids and predicts a molecular mass of 24.7 KDa. It migrates as an approximately 31 KDa band in SDS-PAGE under reducing conditions.
Formulation	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.

Usage Guide von APCS / PTX2 / Serum amyloid P component Protein

Storage	Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution	A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Verwandte Produkte & Themen von APCS / PTX2 / Serum amyloid P component Protein

Related Areas:

Immunology>>Innate Immunity>>Acute Phase Proteins>>Pentraxin 2/PTX2/SAP

Proteins:

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
Serum Amyloid P Component/SAP	Human	APCS / PTX2 / Serum amyloid P component Protein, Recombinant	13610-H08H
Serum Amyloid P Component/SAP	Mouse	Serum amyloid P component/SAP Protein, Recombinant	50113-M08H
Serum Amyloid P Component/SAP	Rat	Serum amyloid P component / APCS Protein, Recombinant	80061-R08H

Antibodies:

Molecule	Application	Description //For Detailed Info. and Price------CLICK!	Cat. No
Mouse Serum Amyloid P Component/SAP	ELISA	Serum amyloid P component / APCS Antibody (Antigen Affinity Purified)	50113-RP02

Beschreibung von APCS / PTX2 / Serum amyloid P component Protein

Serum amyloid P component (SAP), also known as APCS AND Ptx2, is a 25kDa pentameric protein first identified as the pentagonal constituent of pathological deposits called "amyloid". SAP is a member of the pentraxins family, characterised by calcium dependent ligand binding and distinctive flattened β-jellyroll structure similar to that of the legume lectins. SAP has a marked inhibitory effect on the proliferative response of lymphocytes to a variety of T-dependent mitogens. In addition, SAP enhances the formation of active E rosettes, a marker of activated T cells. SAP has certain sequence homology with C-reactive protein (CRP), a classical acute phase response plasma protein, and both of which are evolutionary conserved in all vertebrates and also found in distant invertebrates.

References

Cathcart, E. S. et al.,1967, Biochim. Biophy. Acta. 147: 392-3.
Levo,Y. et al., 1985, Int Arch Allergy Appl Immunol. 77 (3): 322-5.
Emsley, J. et al., 1994, Nature. 367 (6461): 338-45.
Pepys, M. B. et al.,1997,Amyloid-International Journal of Experimental and Clinical Investigation. 4: 274-95.