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VNN2 / Vanin-2 Antikörper

Produkt-Information von VNN2 / Vanin-2 Antikörper

Immunogen

Recombinant Human VNN2 / Vanin-2 protein (Catalog#11728-H08H)

Antibody Type Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform )

Clone ID

018

Ig Type

Rabbit IgG

Formulation 0.2 μm filtered solution in PBS with 5% trehalose
Preparation

This antibody was obtained from a rabbit immunized with purified, recombinant Human VNN2 / Vanin-2 (rh VNN2 / Vanin-2; Catalog#11728-H08H; NP_004656.2; Met 1-Ser 492).

Usage Guide von VNN2 / Vanin-2 Antikörper

Specificity

Human VNN2 / Vanin-2

Western blot This antibody can be used at 1-2 μg/mL with the appropriate secondary reagents to detect Human VNN2 in WB.
Direct ELISA This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human VNN2. The detection limit for Human VNN2 is approximately 0. 078 ng/well.
Storage This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Verwandte Produkte & Themen von VNN2 / Vanin-2 Antikörper

Related Areas:

Enzyme>>Oxidoreductase>>VNN2/Vanin-2

Proteins:
Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
VNN2/Vanin-2 Human VNN2/Vanin-2 Protein, Recombinant 11728-H08H
Antibodies:
Molecule Application Description //For Detailed Info. and Price------CLICK! Cat. No
Human
VNN2/Vanin-2
WB, ELISA VNN2/Vanin-2 Antibody, Rabbit PAb 11728-RP01
Human
VNN2/Vanin-2
WB, ELISA VNN2/Vanin-2 Antibody, Rabbit PAb (Antigen Affinity Purified) 11728-RP02
Human
VNN2/Vanin-2
WB, ELISA VNN2/Vanin-2 Antibody, Mouse MAb 11728-MM04
Human
VNN2/Vanin-2
WB, ELISA VNN2 / Vanin-2 Antibody 11728-R018

Hintergrund von VNN2 / Vanin-2 Antikörper

Vascular non-inflammatory molecule 2, also known as glycosyl-phosphatidyl inositol-anchored protein GPI-80, Vanin-2, Protein FOAP-4 and VNN2, is a cell membrane protein which belongs to the CN hydrolase family and Vanin subfamily. VNN2 is widely expressed with higher expression in spleen and blood. VNN2 is a member of the vanin family of proteins which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. VNN2 is an amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine. It is involved in the thymus homing of bone marrow cells. VNN2 plays a role in transendothelial migration of neutrophils and may regulate beta-2 integrin-mediated cell adhesion, migration and motility of neutrophil.

References

  1. Suzuki K. et al., 1999, J. Immunol. 162: 4277-84.
  2. Martin, F. et al., 2001,Immunogenetics. 53 (4):296-306.
  3. Liu T.et al., 2005, J. Proteome Res. 4: 2070-80.
  4. Jansen P.AM. et al., 2009, J. Invest. Dermatol. 129: 2167-74.

Sino Biological Inc. liefert VNN2 / Vanin-2 Antikörper mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über VNN2 / Vanin-2 Antikörper lesen Sie bitte: http://www.sinobiological.com/VNN2-Vanin-2-Antibody-g-9491.html

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