Vasoactive intestinal peptide / VIP Protein (His Tag)

24.05.2013

Sino Biological Inc. liefert Vasoactive intestinal peptide / VIP Protein (His Tag) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über Vasoactive intestinal peptide / VIP Protein (His Tag) lesen Sie bitte: http://www.sinobiological.com/Vasoactive-intestinal-peptide-VIP-Protein-g-11839.html

Produkt-Information von Vasoactive intestinal peptide / VIP Protein

Synonym	VIP
Protein Construction	A DNA sequence encoding the human VIP (P01282-2) (Met1-Lys169) with a C-terminal polyhistidine tag was expressed.
Source	Human
Expression Host	Human Cells

QC Testing von Vasoactive intestinal peptide / VIP Protein

Purity	(38.2+8+44.3)% as determined by SDS-PAGE	SDS-PAGE: VIP protein
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method
Stability	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal	Ser 21
Molecular Mass	The recombinant human VIP comprises 160 amino acids and has a predicted molecular mass of 18.3 kDa. The apparent molecular mass of the protein is approximately 25, 21 and 15 kDa in SDS-PAGE under reducing conditions.
Formulation	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. Please contact us for any concerns or special requirements.

Usage Guide von Vasoactive intestinal peptide / VIP Protein

Storage	Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution	A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Beschreiung von Vasoactive intestinal peptide / VIP Protein

Vasoactive intestinal peptide, also known as VIP, belongs to the glucagon/secretin superfamily. It is a neuropeptide that functions as a neuromodulator and neurotransmitter. As a potent vasodilator, VIP regulates smooth muscle activity, epithelial cell secretion, and blood flow in the gastrointestinal tract. It also is a chemical messenger which functions as a neurohormone and paracrine mediator, being released from nerve terminals and acting locally on receptor bearing cells. VIP can be detected in many tissues of vertebrates including the gut, pancreas and suprachiasmatic nuclei of the hypothalamus in the brain.

References

Fahrenkrug J. et al., 1982, Br Med Bull. 38 (3): 265-70.
Linder S. et al., 1987, Proc Natl Acad Sci. 84 (2): 605-9.
Kulick RS. et al., 2005, Gen Comp Endocrinol. 142 (3): 267-73.