VAPB / VAP-B Antikörper (Antigen Affinität reinigt)

13.03.2012

Produkt-Information von VAPB / VAP-B Antikörper

Immunogen	Recombinant Human VAPB / VAP-B protein (Catalog#10754-H08E)
Antibody Type	Rabbit Polyclonal Antibody ( Antibody Purification Platform )
Ig Type	Rabbit IgG
Formulation	0.2 μm filtered solution in PBS with 5% trehalose
Preparation	Produced in rabbits immunized with purified, recombinant Human VAPB / VAP-B (rh VAPB / VAP-B; Catalog#10754-H08E; O95292-1; Met 1-Pro 132). VAPB / VAP-B specific IgG was purified by Human VAPB / VAP-B affinity chromatography.

VAPB / VAP-B Antikörper Usage Guide

Specificity	Human VAPB / VAP-B
Western blot	This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human VAPB in WB. Using a DAB detection system, the detection limit for Human VAPB is approximately 0.5 ng/lane under non-reducing conditions and reducing conditions.
Direct ELISA	This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human VAPB. The detection limit for Human VAPB is approximately 0.00975 ng/well.
Storage	This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Verwandte Produkte & Themen von VAPB / VAP-B Antikörper

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Hintergrund von VAPB / VAP-B Antikörper

Vesicle-associated membrane protein-associated protein B / C, also known as VAMP-B/VAMP-C, VAMP-associated protein B/C, VAP-B/VAP-C and VAPB, is a single-pass type IV membrane protein which belongs to theVAMP-associated protein (VAP) family. VAPB contains oneMSP domain. VAPB may play a role in vesicle trafficking. VAPB forms a heterodimer with VAPA. VAPB interacts with VAMP1 and VAMP2. Defects in VAPB are the cause of amyotrophic lateral sclerosis type 8 (ALS8) which is a familial form of amyotrophic lateral sclerosis, a neurodegenerative disorder affecting upper and lower motor neurons and resulting in fatal paralysis. Defects in VAPB are also a cause of spinal muscular atrophy autosomal dominant Finkel type (SMAF) which is characterized by proximal muscle weakness that begins in the lower limbs and then progresses to upper limbs.

References

Nishimura Y., et al., 1999, Biochem. Biophys. Res. Commun. 254: 21-26.
Gevaert K., et al., 2003, Nat. Biotechnol. 21: 566-569.
Hamamoto I., et al., 2005, J. Virol. 79: 13473-13482.
Choudhary C. et al., 2009,Science 325: 834-840.

Sino Biological Inc. liefert VAPB / VAP-B Antikörper (Antigen Affinität reinigt) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über VAPB / VAP-B Antikörper (Antigen Affinität reinigt) lesen Sie bitte: http://www.sinobiological.com/VAPB-VAP-B-Antibody-g-8276.html