ULBP2 / N2DL-2 Antikörper (Antigen Affinity Purified)

22.05.2012

Produkt-Information von ULBP2 / N2DL-2 Antikörper

Immunogen	Recombinant Human ULBP2 / N2DL-2 protein (Catalog#12143-H08H)
Antibody Type	Rabbit Polyclonal Antibody ( Antibody Purification Platform )
Ig Type	Rabbit IgG
Formulation	0.2 μm filtered solution in PBS with 5% trehalose
Preparation	Produced in rabbits immunized with purified, recombinant Human ULBP2 / N2DL-2 (rh ULBP2 / N2DL-2; Catalog#12143-H08H; Q9BZM5; Met 1-Ser 217). ULBP2 / N2DL-2 specific IgG was purified by Human ULBP2 / N2DL-2 affinity chromatography.

Usage Guide von ULBP2 / N2DL-2 Antikörper

Specificity

Human ULBP2 / N2DL-2

Immunochemistry

IHC-P: 0.5-2 μg/mL

ULBP2-renal-carcinoma immunohistochemistry

Immunochemical staining of human ULBP2 in human renal-carcinoma with rabbit polyclonal antibody (1 μg/mL, formalin-fixed paraffin embedded sections).
The left panel: tissue incubated with primary antibody;
The right panel: tissue incubated with the mixture of primary antibody and antigen (recombinant protein).

Western blot

This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human ULBP2 in WB. Using a DAB detection system, the detection limit for Human ULBP2 is approximately 0.5 ng/lane under non-reducing conditions and reducing conditions.

Direct ELISA

This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human ULBP2. The detection limit for Human ULBP2 is approximately 0.039 ng/well.

Storage

This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃.Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Hintergrund von ULBP2 / N2DL-2 Antikörper

NKG2D ligand 2, also known as N2DL-2, NKG2DL2, ALCAN-alpha, Retinoic acid early transcript 1H, UL16-binding protein 2, ULBP2 and N2DL2, is cell membrane protein which belongs to theMHC class I family. ULBP2 / N2DL-2 is expressed in various types of cancer cell lines and in the fetus, but not in normal tissues. ULBP2 / N2DL-2 is a ligand for the NKG2D receptor, together with at least ULBP1 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway.

References

Cosman D. et al., 2001,Immunity 14:123-133.
Cerwenka A., et al., 2003, Tissue Antigens 61:335-343.
Chang,Y.T. et al., 2011, PLoS One. 6 (5):e20029.

Sino Biological Inc. liefert ULBP2 / N2DL-2 Antikörper (Antigen Affinity Purified) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über ULBP2 / N2DL-2 Antikörper (Antigen Affinity Purified) lesen Sie bitte: http://www.sinobiological.com/ULBP2-N2DL-2-Antibody-g-9038.html

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
ULBP2	Human	ULBP2 Protein, Recombinant	12143-H02H
ULBP2	Human	ULBP2 Protein, Recombinant	12143-H08H

Molecule	Application	Description //For Detailed Info. and Price------CLICK!	Cat. No
Human ULBP2	WB, ELISA, IHC-P	ULBP2 / N2DL-2 Antibody (Antigen Affinity Purified)	12143-RP02

ULBP2 / N2DL-2 Antikörper (Antigen Affinity Purified)

Produkt-Information von ULBP2 / N2DL-2 Antikörper

Usage Guide von ULBP2 / N2DL-2 Antikörper

Verwandte Produkte & Themen von ULBP2 / N2DL-2 Antikörper

Hintergrund von ULBP2 / N2DL-2 Antikörper

References