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| Immunogen | Recombinant Human TGM2 / Transglutaminase 2 protein (Catalog#11095-H07B) |
| Antibody Type | Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform ) |
| Clone ID | 013 |
| Ig Type | Rabbit IgG |
| Formulation | 0.2 μm filtered solution in PBS with 5% trehalose |
| Preparation | This antibody was obtained from a rabbit immunized with purified, recombinant Human TGM2 / Transglutaminase 2 (rh TGM2 / Transglutaminase 2; Catalog#11095-H07B; NP_004604.2; Met 1-Ala 687). |
| Specificity | Human TGM2 / Transglutaminase 2 |
| Direct ELISA | This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human TGM2. The detection limit for Human TGM2 is approximately 0.0049 ng/well. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. |
Immunology>>Adhesion Molecule>>Extracellular Matrix Molecule>>Extracellular Matrix Protein>>Transglutaminase 2/TGM2
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| TGM2/Transglutaminase 2 | Human | TGM2/Transglutaminase 2 Protein, Recombinant | 11095-H07B |
| Molecule | Application | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| Human TGM2/Transglutaminase 2 | WB, ELISA | Rabbit Polyclonal Antibody | 11095-RP01 |
| Human TGM2/Transglutaminase 2 | WB, ELISA | Rabbit Polyclonal Antibody (Antigen Affinity Purified) | 11095-RP02 |
| Human TGM2/Transglutaminase 2 | WB | TGM2 / Transglutaminase 2 Antibody | 11095-R001 |
| Human TGM2/Transglutaminase 2 | ELISA | TGM2 / Transglutaminase 2 Antibody | 11095-R013 |
Protein-glutamine gamma-glutamyltransferase 2, also known as Tissue transglutaminase, Transglutaminase C, Transglutaminase-2, and TGM2, is a member of thetransglutaminase superfamily. Human TGM2 is implicated in the pathogenesis of several neurodegenerative disorders including Alzheimer's, Parkinson's and expanded polyglutamine (polyQ) diseases. TGM2 promotes formation of soluble and insoluble high molecular weight aggregates by catalyzing a covalent linkage between peptide-bound Q residues in polyQ proteins and a peptide-bound Lys residue. TGM2 plays a role in cell growth and survival through the anti-apoptosis signaling pathway. Its expression is involved with tumor growth. The expression of TGM2 plays an important role in doxorubicin/cisplatin resistance in breast and ovarian cancer. Down-regulation and over-expression of TGM2 in non-small cell lung cancer (NSCLC) cell suggested a positive correlation of cisplatin sensitivity and TGM2 inhibition. Good responders of cisplatin in NSCLC could be identified by the promoter methylation of TGM2. TGM2 is also useful as a predictive marker for patient prognosis and may be a novel therapeutic target for colorectal cancer (CRC).
Sino Biological Inc. liefert TGM2 / Transglutaminase 2 Antikörper mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.
Weitere Informationen über TGM2 / Transglutaminase 2 Antikörper lesen Sie bitte: http:www.sinobiological.com/TGM2-Transglutaminase-2-Antibody-g-9215.html
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