SLITRK6 Protein (His Tag)

28.11.2012

Sino Biological Inc. liefert SLITRK6 Protein (His Tag) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über SLITRK6 Protein (His Tag) lesen Sie bitte: http://www.sinobiological.com/SLITRK6-Protein-g-9919.html

Produkt-Information von SLITRK6 Protein

Synonym	SLITRK6
Protein Construction	A DNA sequence encoding the human SLITRK6 (Q9H5Y7) (Met1-Ser608) was expressed with a polyhistidine tag at the C-terminus.
Source	Human
Expression Host	Human Cells

QC Testing von SLITRK6 Protein

Purity	> 85% as determined by SDS-PAGE	SDS-PAGE: SLITRK6 protein
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method
Stability	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal	Ser 27
Molecular Mass	The recombinant human SLITRK6 consists of 593 amino acids and predicts a molecular mass of 62.2 KDa. It migrates as an approximately 89 KDa band in SDS-PAGE under reducing conditions.
Formulation	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.

Usage Guide von SLITRK6 Protein

Storage	Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution	A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Beschreibung von SLITRK6 Protein

SLITRK6 is a member of the SLITRK family. SLITRKs are expressed predominantly in neural tissues and have neurite-modulating activity. They share two conserved leucine-rich repeat domains in the extracellular domain. Expression of SlITRK proteins is highly restricted to neural and brain tumor tissues, but varies within the protein family. SLITRK6 is highly expressed in putamen with no expression in cerebral cortex. It also can be detected in adult and fetal lung and fetal liver. Overexpression of SLITRK6 inhibites neurite outgrowth in cultured neurons. In adult brain, SLITRK6 has a critical role in the development of the inner ear neural circuit.

References

Strausberg RL. et al., 2003, Proc Natl Acad Sci. 99 (26): 16899-903.
Wiemann S. et al., 2001, Genome Res. 11 (3): 422-35.
Hartley JL. et al., 2001, Genome Res. 10 (11): 1788-95.