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S100A8 Antikörper

Produkt-Information von S100A8 Antikörper

Immunogen

Recombinant Human S100A8 protein (Catalog#11138-H08B)

Antibody Type Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform )

Clone ID 

101

Ig Type

Rabbit IgG

Formulation 0.2 μm filtered solution in PBS with 5% trehalose
Preparation

This antibody was obtained from a rabbit immunized with purified, recombinant Human S100A8 (rh S100A8; Catalog#11138-H08B; NP_002955.2; Met 1-Glu 93).

Usage Guide von S100A8 Antikörper

Specificity

Human S100A8

Immunochemistry

IHC-P: 1-10 μg/mL

 

S100A8-spleen immunohistochemistry    

Immunochemical staining of human S100A8 in human spleen with rabbit monoclonal antibody (5 μg/mL, formalin-fixed paraffin embedded sections).  
Storage This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃.Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Verwandte Produkte & Themen von S100A8 Antikörper

Related Areas:

Signal Transduction>>Calcium Signaling>>Calcium Binding Protein>>S100 Protein>>S100A8

Cancer>>Cancer Biomarkers>>S100A8

Proteins:
Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
S100A8 Human S100A8 Protein, Recombinant 11138-H08B
S100A8 Human S100A8 Protein, Recombinant 11138-H07E
Antibodies:
Molecule Application Description //For Detailed Info. and Price------CLICK! Cat. No
Human 
S100A8
WB, ELISA S100A8 Antibody, Rabbit PAb 11138-RP01
Human 
S100A8
WB, ELISA S100A8 Antibody, Rabbit PAb (Antigen Affinity Purified) 11138-RP02
Human 
S100A8
WB, ELISA S100A8 Antibody 11138-R101

Hintergrund von S100A8 Antikörper

S100 proteinis a family of low molecular weight protein found in vertebrates characterized by twoEF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that the protein is100%soluble in ammonium sulfateat neutralpH. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from theneural crest, chondrocytes, macrophages, dendritic cells, etc. S100 proteins have been implicated in a variety of intracellular and extracellular functions. They are involved in regulation of protein phosphorylation, transcription factors, the dynamics of cytoskeleton constituents, enzyme activities, cell growth and differentiation, and the inflammatory response.
Human Protein S100-A8, also known as S100 calcium-binding protein A8, Cystic fibrosis antigen, Migration inhibitory factor-related protein 8, S100A8, and CAGA, is a member of the S-100 family. S100A8 plays a role in various functions of myeloid cells by forming a heterocomplex with S100A9. S100A8 and S100A9 are known to be overexpressed in certain species of carcinomas. S100A8 plays an important role in dedifferentiation of thyroid carcinoma possibly by forming a complex with S100A9. S100A8 and S100A9 may also play a key role in inflammation-associated cancer.

References

  1. Donato, R. et al., 2003, Microsc. Res. Tech.60 (6): 540-551.
  2. Gebhardt, C.et al., 2006, Biochem Pharmacol. 72 (11): 1622-31.
  3. Nonaka, D. et al., 2008, J. Cutan. Pathol.35 (11): 1014-1019.
  4. Lim, SY. et al., 2008,J Immunol. 181 (8): 5627-36.

Sino Biological Inc. liefert S100A8 Antikörper mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über S100A8 Antikörper lesen Sie bitte: http://www.sinobiological.com/S100A8-Antibody-g-8778.html

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