Rat HepaCAM2 Protein (His Tag)

28.11.2012

Sino Biological Inc. liefert Rat HepaCAM2 Protein (His Tag) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über Rat HepaCAM2 Protein (His Tag) lesen Sie bitte: http://www.sinobiological.com/HepaCAM2-Protein-g-9924.html

Produkt-Information von HepaCAM2 Protein

Synonym	HepaCAM2
Protein Construction	A DNA sequence encoding the rat HepaCAM2(B5DEN8)(Met1-Leu350) was expressed, fused with a polyhistidine tag at the C-terminus.
Source	Rat
Expression Host	Human Cells

QC Testing von HepaCAM2 Protein

Purity	> 95 % as determined by SDS-PAGE	SDS-PAGE: HepaCAM2 protein
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method
Stability	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal	Leu 33
Molecular Mass	The recombinant rat HepaCAM2 comprises 329 amino acids and predicts a molecular mass of 36.7 kDa. The apparent molecular mass of the recombinant protein is approximately 60 kDa in SDS-PAGE under reducing conditions due to glycosylation.
Formulation	Lyophilized from sterile PBS, pH7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.

Usage Guide von HepaCAM2 Protein

Storage	Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution	A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Beschreibung von HepaCAM2 Protein

HepaCAM2, together with HEPACAM1, are cell adhesion molecules. They are cell adhesion molecules that belong to the immunoglobulin family. HEPACAM1 modulates cell adhesion and migration. It is involved in cell-extracellular matrix interactions and cell growth control of cancer cells. HepaCAM2 contains 2 Ig-like C2-type (immunoglobulin-like) domains. It is widely expressed. HepaCAM2 is decreased in metastatic canine mammary carcinoma and their metastases. While in normal glands, HepaCAM2’s expression levels remain the same.

References

Moh MC. et al., 2008, Carcinogenesis. 29 (12): 2298-305.
Moh MC. et al., 2005, J Biol Chem. 280 (29): 27366-74.
Chung Moh M. et al., 2005, J Hepatol. 42 (6): 833-41.