Rat CD302 / CLEC13A Protein

Sino Biological Inc. liefert Rat CD302 / CLEC13A Protein mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über Rat CD302 / CLEC13A Protein lesen Sie bitte: http://www.sinobiological.com/CD302-CLEC13A-Protein-g-10050.html

Produkt-Information von CD302 / CLEC13A Protein

QC Testing von CD302 / CLEC13A Protein

Purity	> 95% as determined by SDS-PAGE	SDS-PAGE: CD302 protein
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method
Stability	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal	Asp 21
Molecular Mass	The recombinant rat CD302/Fc is a disulfide-linked homodimer. The reduced monomer comprises 386 amino acids and has a predicted molecular mass of 43.7 kDa. The apparent molecular mass of the protein is approximately 47 kDa in SDS-PAGE under reducing conditions.
Formulation	Lyophilized from sterile PBS, pH7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.

Usage Guide von CD302 / CLEC13A Protein

Verwandte Produkte & Themen von CD302 / CLEC13A Protein

Immunology>>Cluster of Differentiation>>Monocyte/Macrophage CD Antigen>>Macrophage Markers>>CD302/CLEC13A

Immunology>>Adhesion Molecule>>Lectin>>CD302/CLEC13A

Beschreibung von CD302 / CLEC13A Protein

CD302, also known as C-type lectin domain family 13 member A (CLEC13A), or Type I transmembrane C-type lectin receptor DCL-1, is an unconventional C-type lectin that may play roles not only in endocytosis/phagocytosis but also in APC adhesion and migration. DCL-1 protein was highly conserved among the human, mouse, and rat orthologs. DCL-1 CP contains several putative motifs, including a Tyr-based internalization, a cluster of acidic amino acids, and Ser and Tyr phosphorylation motifs, suggesting that DCL-1 CP mediates not only endocytosis and late endosome targeting but also signaling.

References

1. Skinnider B. et al., 2002, Blood. 99(12): 4283-97.
2. Kato M. et al., 2007, J Immunol. 179(9): 6052-63.