Prostatic Acid Phosphatase / ACPP Antikörper

28.08.2012

Produkt-Information von Prostatic Acid Phosphatase / ACPP Antikörper

Immunogen	Recombinant Human Prostatic Acid Phosphatase / ACPP protein (Catalog#10959-H08H)
Antibody Type	Mouse Monoclonal Antibody ( Mouse mAb Service Platform )
Clone ID	03
Ig Type	Mouse IgG1
Formulation	0.2 μm filtered solution in PBS with 5% trehalose
Preparation	This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Prostatic Acid Phosphatase / ACPP (rh Prostatic Acid Phosphatase / ACPP; Catalog#10959-H08H; NP_001127666.1; Met 1-Lys 382). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.

Usage Guide von Prostatic Acid Phosphatase / ACPP Antikörper

Specificity	Human Prostatic Acid Phosphatase / ACPP
	No cross-reactivity in ELISA with Human cell lysate (293 cell line)
Western blot	This antibody can be used at 1-2 μg/mL with the appropriate secondary reagents to detect Human ACPP in WB.
Direct ELISA	This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect Human ACPP.
Storage	This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

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Proteins:

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
Prostatic Acid Phosphatase/ACPP	Human	Prostatic Acid Phosphatase/ACPP Protein, Recombinant	10959-H08H
Prostatic Acid Phosphatase/ACPP	Mouse	ACPP / PSAP Protein, Recombinant	51018-M08H

Antibodies:

Molecule	Application	Description //For Detailed Info. and Price------CLICK!	Cat. No
Human Prostatic Acid Phosphatase/ACPP	WB, ELISA	Prostatic Acid Phosphatase / ACPP Antibody	10959-MM03
Human Prostatic Acid Phosphatase/ACPP	ELISA	Prostatic Acid Phosphatase / ACPP Antibody	10959-MM06
Human Prostatic Acid Phosphatase/ACPP	WB, ELISA	Prostatic Acid Phosphatase/ACPP Antibody (Antigen Affinity Purified)	10959-RP02

Hintergrund von Prostatic Acid Phosphatase / ACPP Antikörper

Prostatic acid phosphatase, also known as ACPP, is a secreted and a single-pass type I membrane protein which belongs to thehistidine acid phosphatase family. ACPP / PSAP is an enzyme produced by the prostate. It may be found in increased amounts in men who have prostate cancer or other diseases. The highest levels of ACPP / PSAP are found in metastasized prostate cancer. Diseases of the bone, such as Paget's disease or hyperparathyroidism, diseases of blood cells, such as sickle-cell disease or multiple myeloma or lysosomal storage diseases, such as Gaucher's disease, will show moderately increased levels. ACPP / PSAP was used to monitor and assess progression of prostate cancer until the introduction of prostate specific antigen (PSA), which has now largely displaced it. ACPP / PSAP has a role in prognosticating intermediate and high-risk prostate cancer, it has led to renewed interest in this marker. Its physiological function may be associated with the liquefaction process of semen. ACPP / PSAP may play an important role in the transmission of HIV. ACPP / PSAP forms fibers made of amyloid. There fibers capture HIV virions promoting their attachment to target cells. The association of ACPP / PSAP with HIV may increase the ability of the virus to infect human cells "by several orders of magnitude."ACPP / PSAP may be a future target of efforts to combat the spread of HIV infection.

References

Genega EM, et al., 2000, Mod. Pathol.13 (11): 1186-91.
Taira A, et al.,2007, Oncology. 21 (8): 1003-10.
Munch J, et al., 2007, Cell131 (6): 1059-71.
Zylka MJ, et al.,2008, Neuron. 60 (1): 111-22.

Sino Biological Inc. liefert Prostatic Acid Phosphatase / ACPP Antikörper mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über Prostatic Acid Phosphatase / ACPP Antikörper lesen Sie bitte: http://www.sinobiological.com/KIM-1-TIM1-HACVR1-Antibody-g-9492.html