PFD2 / PFDN2 Protein (His Tag)

26.03.2013

Sino Biological Inc. liefert PFD2 / PFDN2 Protein (His Tag) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über PFD2 / PFDN2 Protein (His Tag) lesen Sie bitte: http://www.sinobiological.com/PFDN2-Protein-Antibody-a-5742.html

Produkt-Information von PFD2 / PFDN2 Protein

Synonym	PFDN2, PFD2
Protein Construction	A DNA sequence encoding the mature form of human PFDN2 (Q9UHV9) (Met1-Ser154) was expressed with a polyhistide tag at the N-terminus.
Source	Human
Expression Host	E.coli

QC Testing von PFD2 / PFDN2 Protein

Purity	> 95 % as determined by SDS-PAGE	SDS-PAGE: PFD2 protein
Endotoxin	Please contact us for more information.
Stability	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal	His
Molecular Mass	The recombinant human PFDN2 consists of 169 amino acids and predicts a molecular mass of 18.5 KDa. It migrates as an approximately 18-20 KDa band in SDS-PAGE under reducing conditions.
Formulation	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. Please contact us for any concerns or special requirements.

Usage Guide von PFD2 / PFDN2 Protein

Storage	Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution	A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Beschreibung von PFD2 / PFDN2 Protein

PFD2, also known as PFDN2, is a member of the prefoldin beta subunit family. PFD2 binds to a nascent polypeptide chain and promotes folding in an setting in which there are many competing pathways for nonnative proteins. PFD2 is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. PFD2 binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it.

References

Gerhard DS. et al., 2004, Genome Res. 14 (10B): 2121-7.
Bauch A. et al., 2004, Nat Cell Biol. 6 (2): 97-105.
Nogaj LA. et al., 2005, Plant Physiol. 139 (1): 389-96.