PDRG1 / C20orf126 Protein (His Tag)

27.05.2013

Sino Biological Inc. liefert PDRG1 / C20orf126 Protein (His Tag) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über PDRG1 / C20orf126 Protein (His Tag) lesen Sie bitte:http://www.sinobiological.com/PDRG1-C20orf126-Protein-Antibody-a-6208.html

Produkt-Information von PDRG1 / C20orf126 Protein

Synonym	PDRG1, C20orf126, PDRG
Protein Construction	A DNA sequence encoding the human PDRG1 (Q9NUG6) (Met1-Gly133) was expressed with a polyhistidine tag at the N-terminus.
Source	Human
Expression Host	E.coli

QC Testing von PDRG1 / C20orf126 Protein

Purity	> 95 % as determined by SDS-PAGE	SDS-PAGE: PDRG1 protein
Endotoxin	Please contact us for more information.
Stability	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal	His
Molecular Mass	The recombinant human PDRG1 consists of 148 amino acids and predicts a molecular mass of 17.3 KDa. It migrates as an approximately 12 KDa band in SDS-PAGE under reducing conditions.
Formulation	Lyophilized from sterile PBS, 10% Glycerol, pH 7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. Please contact us for any concerns or special requirements.

Usage Guide von PDRG1 / C20orf126 Protein

Storage	Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution	A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Beschreibung von PDRG1 / C20orf126 Protein

PDRG1, also known as C20orf126, belongs to the prefoldin subunit beta family. It is predominantly expressed in normal testis and exhibits reduced but detectable expression in other organs. PDRG1 may play a role in chaperone-mediated protein folding. PDRG1 is overexpressed in tumors relative to normal tissues. Its expression is upregulated in multiple malignancies including cancers of the colon, rectum, ovary, lung, stomach, breast and uterus when compared to their respective matched normal tissues. Thus PDRG1 is a high-value novel tumor marker that could play a role in cancer development and/or progression.

References

Kim W. et al., 2011, Mol Cell. 44 (2): 325-40.
Havugimana PC. et al., 2012, Cell. 150 (5): 1068-81.
Jiang L. et al., 2011, Cancer Biol Ther. 11 (6): 567-73.