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OLR1 / LOX1 Antikörper

Produkt-Information von OLR1 / LOX1 Antikörper

Immunogen

Recombinant Human OLR1 / LOX1 protein (Catalog#10585-H07H)

Antibody Type Rabbit Polyclonal Antibody ( Antibody Purification Platform )
Ig Type

Rabbit IgG

Formulation 0.2 μm filtered solution in PBS with 5% trehalose
Preparation

Produced in rabbits immunized with purified, recombinant Human OLR1 / LOX1 (rh OLR1 / LOX1; Catalog#10585-H07H; P78380; Ser 61-Gln 273). Total IgG was purified by Protein A affinity chromatography.

Usage Guide von OLR1 / LOX1 Antikörper

Specificity

Human OLR1 / LOX1

Western blot This antibody can be used at 1-2 μg/mL with the appropriate secondary reagents to detect Human LOX1 in WB. Using a DAB detection system, the detection limit for Human LOX1 is approximately 0.5 ng/lane under non-reducing conditions and reducing conditions.
Direct ELISA This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect Human LOX1. The detection limit for Human LOX1 is approximately 0.00975 ng/well.
Storage This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Verwandte Produkte & Themen von OLR1 / LOX1 Antikörper

Related Areas:

Immunology>>Adhesion Molecule>>Lectin>>OLR1

Proteins:
Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
OLR1 Human OLR1 / LOX1 Protein,Recombinant 10585-H07H
Antibodies:
Molecule Application Description //For Detailed Info. and Price------CLICK! Cat. No
Human OLR1 WB, ELISA OLR1 / LOX1 Antibody 10585-RP01

Hintergrund von OLR1 / LOX1 Antikörper

Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1) also known as lectin-type oxidized LDL receptor 1 (LOX-1) is a receptor protein which belongs to the C-type lectin superfamily. Lectin-like oxidized LDL receptor-1 (LOX-1) was isolated from an aortic endothelial cell, and recently it has been discovered in macrophages and vascular smooth muscle cells in artery vessels. The expression of LOX-1 is inducted by inflammatory stimuli, so LOX-1 is thought to be involved in the development of atherosclerotic lesions. It is an important cell surface receptor for the progression of atherosclerosis. LOX-1 is a multi-ligand receptor originally identified as the endothelial oxidized LDL receptor. LOX-1 expression is also induced in smooth muscle cells in response to proinflammatory and oxidative stimuli. LOX-1 may play an important role in the progression of vulnerable carotid plaque and might regulate vulnerable plaque formation in cooperation with MMPs and TIMP-2.

References

  1. Hinagata J. et al., 2006, Cardiovasc Res. 69 (1): 263-71.
  2. Melan MA. et al., 1994, Plant Physiol. 105 (1): 385-393.
  3. Saito A. et al., 2010, Acta Neurochir (Wien). 152 (4): 589-95.

Sino Biological Inc. liefert OLR1 / LOX1 Antikörper mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über OLR1 / LOX1 Antikörper lesen Sie bitte: http:www.sinobiological.com/OLR1-LOX1-Antibody-g-9278.html

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