NDRG1 Protein (His Tag)

22.04.2013

Sino Biological Inc. liefert NDRG1 Protein (His Tag) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über NDRG1 Protein (His Tag) lesen Sie bitte: http://www.sinobiological.com/NDRG1-CAP43-Protein-Antibody-a-5866.html

Produkt-Information von NDRG1 Protein

Synonym	NDRG1, CAP43, DRG, RTP
Protein Construction	A DNA sequence encoding the human NDRG1 (Q92597) (Met1-Cys394) was expressed with a polyhistidine tag at the C-terminus.
Source	Human
Expression Host	E.coli

QC Testing von NDRG1 Protein

Purity	> 85 % as determined by SDS-PAGE	SDS-PAGE: NDRG1 protein
Endotoxin	Please contact us for more information.
Stability	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal	Met
Molecular Mass	The recombinant human NDRG1 consists of 401 amino acids and predicts a molecular mass of 43.8 KDa. It migrates as an approximately 43 KDa band in SDS-PAGE under reducing conditions.
Formulation	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. Please contact us for any concerns or special requirements.

Usage Guide von NDRG1 Protein

Storage	Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution	A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Beschreibung von NDRG1 Protein

NDRG1 gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. NDRG1 is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. NDRG1 is necessary for p53-mediated caspase activation and apoptosis. Mutations in NDRG1 gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. NDRG1 is a stress-responsive protein involved in hormone responses, cell growth, and differentiation. It acts as a tumor suppressor in many cell types.

References

Kachhap SK. et al., 2007, PLoS ONE. 2 (9): e844.
Zhang J. et al., 2008, Gene. 417 (1-2): 5-12.
Kokame K. et al., 1997, J Biol Chem. 271 (47): 29659-65.
NDRG1 (CAP43) related areas, pathways, and other information