N-Cadherin / CD325 / CDH2 Antikörper

22.05.2012

Produkt-Information von N-Cadherin / CD325 / CDH2 Antikörper

Immunogen	Recombinant Human N-Cadherin / CD325 / CDH2 protein (Catalog#11039-H08H)
Antibody Type	Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform )
Clone ID	014
Ig Type	Rabbit IgG
Formulation	0.2 μm filtered solution in PBS with 5% trehalose
Preparation	This antibody was obtained from a rabbit immunized with purified, recombinant Human N-Cadherin / CD325 / CDH2 (rh N-Cadherin / CD325 / CDH2; Catalog#11039-H08H; NP_001783.2; Met 1-Ala 724).

Usage Guide von N-Cadherin / CD325 / CDH2 Antikörper

Specificity

Human N-Cadherin / CD325 / CDH2

Immunochemistry

ICC/IF: 5-15 μg/mL

CDH2-R014-5ug-HeLa-IF Immunofluorescence

Immunofluorescence staining of human CDH2 in HeLa cells with rabbit monoclonal antibody (5 μg/mL). The image showing membrane staining of HeLa cells.

Western blot

This antibody can be used at 1-2 μg/mL with the appropriate secondary reagents to detect Human CDH2 in WB.

Direct ELISA

This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human CDH2. The detection limit for Human CDH2 is approximately 0.00245 ng/well.

Storage

This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃.Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Verwandte Produkte & Themen von N-Cadherin / CD325 / CDH2 Antikörper

Related Areas:

Neuroscience>>Synaptic Protein>>N-Cadherin/CDH2/CD325

Stem Cell>>Mesenchymal Stem Cell (MSC)>>Mesenchymal Stem Cell Marker>>N-Cadherin/CDH2/CD325

Cancer>>Angiogenesis>>Adhesion Molecules in Angiogenesis>>N-Cadherin/CDH2/CD325

Immunology>>Adhesion Molecule>> Cadherin>>N-Cadherin/CDH2/CD325

Immunology>>Cluster of Differentiation>>N-Cadherin/CDH2/CD325

Proteins:

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
N-Cadherin/CD325/CDH2	Human	N-Cadherin/CD325/CDH2 Protein, Recombinant	11039-H08H

Antibodies:

Molecule	Application	Description //For Detailed Info. and Price------CLICK!	Cat. No
Human N-Cadherin/CD325/CDH2	FCM	N-Cadherin / CD325 / CDH2 Antibody	11039-R001
Human N-Cadherin/CD325/CDH2	WB, ELISA	N-Cadherin / CD325 / CDH2 Antibody	11039-R014
Human N-Cadherin/CD325/CDH2	WB, ELISA	N-Cadherin / CD325 / CDH2 Antibody	11039-R017
Human N-Cadherin/CD325/CDH2	WB, ELISA, FCM	N-Cadherin / CD325 / CDH2 Antibody	11039-R020

Hintergrund von N-Cadherin / CD325 / CDH2 Antikörper

Cadherins are calcium dependent cell adhesion proteins, and they preferentially interact with themselves in a homophilic manner in connecting cells. Human cadherin 2, type 1, N-cadherin (neuronal) (NCAD), also known as CDH2, is a single-pass tranmembrane protein and a cadherin containing 5 cadherin domains. N-cadherin displays a ubiquitous expression pattern but with different expression levels between endocrine cell types. CDH2 (NCAD) has been shown to play an essential role in normal neuronal development, which is implicated in an array of processes including neuronal differentiation and migration, and axon growth and fasciculation. In addition, N-cadherin expression was upregulated in human HSC during activation in culture, and function or expression blocking of N-cadherin promoted apoptosis. During apoptosis, N-cadherin was cleaved into 20-100 kDa fragments. N-cadherin cleavage occurred at a higher level in glioblastoma cells than in non-neoplastic astrocytes.

References

LaMora A. et al., 2009, Neuroscience. 159: 1175-1184.
Chauvet N. et al., 2009, J Endocrinol. 202: 375-387.
Hartland S.N. et al., 2009, Liver Int. 29: 966-978.
Kohutek Z.A. et al., 2009, J Neurosci. 29: 4605-4615.

Sino Biological Inc. liefert N-Cadherin / CD325 / CDH2 Antikörper mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über N-Cadherin / CD325 / CDH2 Antikörper lesen Sie bitte: http://www.sinobiological.com/N-Cadherin-CD325-CDH2-Antibody-g-8865.html