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Mouse VEGF-D / VEGFD / FIGF Protein (His Tag)

Sino Biological Inc. liefert Mouse VEGF-D / VEGFD / FIGF Protein (His Tag) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über Mouse VEGF-D / VEGFD / FIGF Protein (His Tag) lesen Sie bitte: http://www.sinobiological.com/VEGF-D-VEGFD-FIGF-Protein-g-10030.html

Produkt-Information von VEGF-D / VEGFD / FIGF Protein

Synonym

FIGF, Vegfd

Protein Construction

A DNA sequence encoding the mouse FIGF (P97946) (Phe98-Ser206) was expressed with a C-terminal polyhistidine tag.

Source Mouse
Expression Host Human Cells

QC Testing von VEGF-D / VEGFD / FIGF Protein

Purity > 95% as determined by SDS-PAGE SDS-PAGE:
SDS-PAGE

VEGF-D protein

Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Stability Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal Phe 98
Molecular Mass

The recombinant mouse FIGF comprises 120 amino acids and has a predicted molecular mass of 14 kDa. The apparent molecular mass of the protein is approximately 22 kDa in SDS-PAGE under reducing conditions due to glycosylation.

Formulation Lyophilized from sterile PBS, pH7.4
  1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.

Usage Guide von VEGF-D / VEGFD / FIGF Protein

Storage Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Verwandte Produkte & Themen von VEGF-D / VEGFD / FIGF Protein

Related Areas:

Cancer>>Growth factor & Receptor>>VEGF & Receptor>>FIGF/VEGF-D

Proteins:
Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
FIGF/VEGF-D Human FIGF/VEGF-D Protein, Recombinant 10557-H08H
FIGF/VEGF-D Mouse

VEGF-D / VEGFD / FIGF Protein, Recombinant

50157-M01H
FIGF/VEGF-D Mouse

VEGF-D / VEGFD / FIGF Protein, Recombinant

50157-M08H
FIGF/VEGF-D Rat

VEGF-D / VEGFD / FIGF Protein, Recombinant

80104-R01H
Antibodies:
Molecule Application Description //For Detailed Info. and Price------CLICK! Cat. No
Human
FIGF/VEGF-D
ELISA Rabbit Monoclonal Antibody 10557-R106
Human
FIGF/VEGF-D
WB, ELISA FIGF/VEGF-D Antibody, Rabbit MAb 10557-R201
Human
FIGF/VEGF-D
WB, ELISA Rabbit Polyclonal Antibody (Antigen Affinity Purified) 10557-RP01
Human
FIGF/VEGF-D
WB, ELISA Rabbit Polyclonal Antibody 10557-RP02

Beschreibung von VEGF-D / VEGFD / FIGF Protein

Vascular endothelial growth factor D (VEGF-D), also known as C-fos induced growth factor (FIGF), is a vascular endothelial growth factor. This secreted protein is a member of the platelet derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and performs activities in angiogenesis, lymphangiogenesis, and endothelial cell growth. Human VEGF-D is expressed in adult lung, heart, muscle, and small intestine, and is most abundantly expressed in fetal lungs and skin. It is structurally and functionally similar to VEGF-C, and is secreted as a non-covelent homodimer in a antiparallel fashion. VEGF-D undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. Like VEGFC, it may particularly be involed in the formation of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults.

References

  1. Achen MG. et al., 1998, Proc Natl Acad Sci. 95 (2): 548-53.
  2. Stacker SA. et al., 1999, J Biol Chem. 274: 32127-36.
  3. Baldwin ME. et al., 2001, J Biol Chem. 276: 19166-71.
  4. McColl BK. et al., 2003, J Exp Med. 198: 863-8.
  5. Roy H. et al., 2006, FEBS Lett. 580: 2879-87.
  6. Otrock ZH. et al., 2007, Blood Cells Mol Dis. 38: 258-68.
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