Mouse FCRL1 / IFGP1 Protein (His Tag)

Sino Biological Inc. liefert Mouse FCRL1 / IFGP1 Protein (His Tag) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

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Produkt-Information von FCRL1 / IFGP1 Protein

QC Testing von FCRL1 / IFGP1 Protein

Purity	> 95% as determined by SDS-PAGE	SDS-PAGE: FCRL1 protein
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method
Stability	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal	Ala 17
Molecular Mass	The recombinant mouse FCRL1 comprises 199 amino acids and has a predicted molecular mass of 21.6 kDa. The apparent molecular mass of the protein is approximately 42-47 kDa in SDS-PAGE under reducing conditions due to glycosylation.
Formulation	Lyophilized from sterile PBS, pH7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.

Usage Guide von FCRL1 / IFGP1 Protein

Verwandte Produkte & Themen von FCRL1 / IFGP1 Protein

Immunology>>Fc Receptor>>FCRL1/FCRH1

Beschreibung von FCRL1 / IFGP1 Protein

Fc receptor-like protein 1, also known as FcR-like protein 1, Fc receptor homolog 1, IFGP family protein 1, Immune receptor translocation-associated protein 5 and FCRL1, is a single-pass type I  membrane protein which contains three Ig-like C2-type (immunoglobulin-like) domains. It is a cell-surface membrane protein belonging to FCRL family and is preferentially expressed on B cells. FCRL1 is primarily expressed in secondary lymphoid tissues by mature subsets of B cells. It is detected in spleen, lymph node, heart, skeletal muscle, kidney, liver and placenta. FCRL1 is specifically expressed by mature B lineage cells with higher expression in naive versus memory B cells (at protein level). Human Fc receptor-like molecules (FCRL1, FCRL2, FCRL3, FCRL4, FCRL5) have tyrosine-based immunoregulatory potential and are expressed by B-lineage subpopulations. FCRL1 may function as an activating coreceptor in B cells. It may also function in B cells activation and differentiation.

References

1. Du X. et al., 2008, Blood. 111 (1): 338-43.
2. Kazemi T. et al., 2008, Int J Cancer. 123 (9): 2113-9.
3. Baranov K. et al., 2008, J Immunol Methods. 332 (1-2): 73-81.