Mouse CNTN3 / Contactin-3 Protein (His Tag)

16.04.2012

Produkt-Information von CNTN3 / Contactin-3 Protein

Synonym	Pang
Protein Construction	A DNA sequence encoding the mouse CNTN3 (NP_032805.2) (Met1-Gly 1001) was expressed, with a C-terminal polyhistidine tag.
Source	Mouse
Expression Host	Human Cells

QC Testing von CNTN3 / Contactin-3 Protein

Purity	> 95 % as determined by SDS-PAGE	SDS-PAGE: CNTN3 / Contactin-3 protein
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method
Stability	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal	Glu 20
Molecular Mass	The recombinant mouse CNTN3 consists of 993 amino acids and predicts a molecular mass of 110 KDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rmCNTN3 is approximately 140-150 KDa as a result of glycosylation.
Formulation	Lyophilized from 0.2μm filtered solution of PBS, pH7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.

Usage Guide von CNTN3 / Contactin-3 Protein

Storage	Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution	A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Verwandte Produkte & Themen von CNTN3 / Contactin-3 Protein

Related Areas:

Immunology>>Adhesion Molecule>> Cell Adhesion Molecule (IgSF CAM) >>Contactin 3/CNTN3

Proteins:

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat No
Contactin 3/CNTN3	Human	Contactin 3/CNTN3/Fc Protein, Recombinant	10174-H02H
Contactin 3/CNTN3	Human	Contactin 3/CNTN3 Protein, Recombinant	10174-H08H

Antibodies:

Molecule	Application	Description //For Detailed Info. and Price------CLICK!	Cat No
Human Contactin 3/CNTN3	WB, ELISA	Mouse Monoclonal Antibody	10174-MM01
Human Contactin 3/CNTN3	WB, ELISA	Contactin 3/CNTN3 Antibody, Rabbit MAb	10174-R006
Human Contactin 3/CNTN3	WB, ELISA	Rabbit Polyclonal Antibody	10174-RP02
Human Contactin 3/CNTN3	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)	10174-RP03

Beschreibung von CNTN3 / Contactin-3 Protein

The brain-derived axon-associated cell adhesion molecule BIG-1, also known as CNTN3 or PANG (plasmacytoma-associated neuronal glycoprotein) ,belongs to the contactin family consisting of six members (CNTN1/F3, CNTN2/TAG-1, CNTN3/BIG-1, CNTN4/BIG-2, CNTN5/NB-2 and CNTN6/NB-3). CNTN3 is a member of the immunoglobulin (Ig)superfamily with six Ig-like domains, four fibronectin type I II-like repeats, and a GPI-anchoring domain. The expression pattern of CNTN3 is developmentally regulated with the highest level in the adult brain , and restricted to subsets of neurons such as Purkinje cells of the cerebellum, granule cells of the dentate gyrus, and neurons in the superficial layers of the cerebral cortex. It has been suggested that BIG-1 has a neurite outgrowth-promoting activity ,and play an important role in the formation and maintenance of specific neuronal networks in the brain together with other contactin members.

References

Yoshihara Y. et al., 1994, Neuron. 13: 415-26.
Yoshihara Y. et al., 1995, J Neurobiol. 28: 51-69.
Connelly M.A., et al., 1994, Proc Natl Acad Sci. 91: 1337-41.
Mock BA. et al., 1996, Genomics. 34: 226-8.

Sino Biological Inc. liefert Mouse CNTN3 / Contactin-3 Protein (His Tag) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

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