Mouse CNDP1 Protein (His Tag)

30.03.2012

Produkt-Information von CNDP1 Protein

Synonym	AI746433, Cn1
Protein Construction	A DNA sequence encoding the mouse CNDP1 (Q8BUG2) (Met 1-Tyr 492) was expressed, with an N-terminal signal peptide and a C-terminal polyhistidine tag.
Source	Mouse
Expression Host	Human Cells

QC Testing von CNDP1 Protein

Purity	> 93 % as determined by SDS-PAGE	SDS-PAGE: CNDP1 protein
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method
Stability	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal	Met 1
Molecular Mass	The secreted recombinant mouse CNDP1 comprises 503 amino acids and has a calculated molecular mass of 56.5 kDa. As a result of glycosylation, the apparent molecular mass of the recombinant protein is approximately 55 kDa in SDS-PAGE under reducing conditions.
Formulation	Lyophilized from 0.2μm filtered solution of PBS, pH7.4 Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.

CNDP1 Protein Usage Guide

Storage	Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution	A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Verwandte Produkte & Themen von CNDP1 Protein

Related Areas:

Enzyme>>Protease & Regulator>>Metalloprotease & Regulator>>CNDP1

Proteins:

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat No
CNDP1	Human	CNDP1/Fc Protein, Recombinant	10077-H03H
CNDP1	Human	CNDP1 Protein, Recombinant	10077-H08H
CNDP1	Mouse	CNDP1 Protein, Recombinant	50959-M08H

Antibodies:

Molecule	Application	Description //For Detailed Info. and Price------CLICK!	Cat No
Human CNDP1	ELISA	Mouse Monoclonal Antibody Mab	10077-MM01
Human CNDP1	WB	Mouse Monoclonal Antibody Mab	10077-MM02
Human CNDP1	ELISA	Rabbit Polyclonal Antibody	10077-RP03
Human CNDP1	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)	10077-RP04
Mouse CNDP1	WB, ELISA	Rabbit Monoclonal Antibody Mab	10077-R001

Beschreibung von CNDP1 Protein

CNDP1, also known as glutamate carboxypeptidase-like protein 2 (CPGL-2) or carnosinase 1 (CN1), is a member of the M20 metalloprotease family. This protein is a secreted homodimeric dipeptidase that specifically hydrolyzes L-carnosine, and is identified as human carnosinase expressed in the brain. The CN1 gene contains trinucleotide (CTG) repeat length polymorphism in the coding region, which has been demonstrated to be associated with susceptibility to developing diabetic nephropathy, for carnosine protects against the adverse effects of high glucose levels on renal cells. In addition, this enzyme is also suggested to be implicated in the actions of neuroprotection and neurotransmiting.

References

Teufel Mm. et al., 2004, J Biol Chem. 278: 6521-32.
Riedl E. et al., 2007, Diabetes. 56: 2410-3.
Sauerhofer S. et al., 2007, Diabetes. 56: 2425-32.

Sino Biological Inc. liefert Mouse CNDP1 Protein (His Tag) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

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