LSM1 Protein (His Tag)

25.03.2013

Sino Biological Inc. liefert LSM1 Protein (His Tag) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über LSM1 Protein (His Tag) lesen Sie bitte: http://www.sinobiological.com/LSM1-Protein-Antibody-a-5745.html

Produkt-Information von LSM1 Protein

Synonym	LSM1, CASM
Protein Construction	A DNA sequence encoding the mature form of human LSM1 (O15116) (Met1-Tyr133) was expressed with a polyhistide tag at the N-terminus.
Source	Human
Expression Host	CHO Stable Cell

QC Testing von LSM1 Protein

Purity	> 85 % as determined by SDS-PAGE	SDS-PAGE: LSM1 protein
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method
Stability	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal	His
Molecular Mass	The recombinant human LSM1 consists of 148 amino acids and predicts a molecular mass of 17 KDa. It migrates as an approximately 19-21 KDa band in SDS-PAGE under reducing conditions.
Formulation	Lyophilized from sterile 10% glycerol, 20mM Tris, 100mM NaCl, pH 7.5. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. Please contact us for any concerns or special requirements.

Usage Guide von LSM1 Protein

Storage	Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution	A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Beschreibung von LSM1 Protein

LSM1 is a Sm-like protein. Sm-like proteins include the Sm sequence motif, which consists of two regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing. Sm-like proteins can be detected in a variety of organisms based on sequence homology with the Sm protein family. LSM1 facilitates RNA protein interactions and structural modifications which are required during ribosomal subunit assembly. LSM1 also plays a role in replication-dependent histone mRNA degradation and binds specifically to the 3''-terminal U-tract of U6 snRNA.

References

Shimizu Y. et al., 1997, Am J Hematol. 54 (1): 1-11.
Graber MW. et al., 1997, Cancer Res. 57 (14): 2961-5.
Séraphin B. et al., 1999, EMBO J. 18 (12): 3451-62.