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LCN2 / NGAL Antikörper

Produkt-Information von LCN2 / NGAL Antikörper

Immunogen

Recombinant Mouse LCN2 / NGAL protein (Catalog#50060-M08H)

Antibody Type Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform )

Clone ID 

211

Ig Type

Rabbit IgG

Formulation 0.2 μm filtered solution in PBS with 5% trehalose
Preparation

This antibody was obtained from a rabbit immunized with purified, recombinant Mouse LCN2 / NGAL (rM LCN2 / NGAL; Catalog#50060-M08H; NP_032517.1; Met 1-Asn 200).

Usage Guide von LCN2 / NGAL Antikörper

Specificity

Mouse LCN2 / NGAL

 

No cross-reactivity in ELISA with

Human LCN2

Western blot This antibody can be used at 1-2 μg/mL with the appropriate secondary reagents to detect Mouse LCN2 in WB. Using a DAB detection system, the detection limit for Mouse LCN2 is approximately 5 ng/lane under non-reducing conditions and 20 ng/lane under reducing conditions.
Direct ELISA This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Mouse LCN2. The detection limit for Mouse LCN2 is approximately 0.3125 ng/well.
Storage This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃.Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Verwandte Produkte & Themen von LCN2 / NGAL Antikörper

Related Areas:
Proteins:
Antibodies:

Hintergrund von LCN2 / NGAL Antikörkper

Neutrophil gelatinase-associated lipocalin (NGAL), also known as LCN2, a constituent of neutrophil granules, is a member of the lipocalin family of binding proteins. Mouse LCN2 gene was first isolated from mouse kidney, and is detected in lung, spleen, uterus, vagina and epididymis. LCN2 plays a role in a variety of processes including cell differentiation, tumorigenesis, and apoptosis. It is indicted that NGAL exerts bacteriostatic effects, which are explained by its ability to capture and deplete siderophores, a small iron-binding molecules synthesized by certain bacteria as a means of iron acquisition. Further, Acting as a growth and differentiation factor in multiple cell types, some of the activity of LCN2 is enhanced in the presence of siderophore: iron complexes.

References

  1. Kjeldsen L. et al., 1993, J Biol Chem. 268 (14): 10425-32.
  2. Goetz DH. et al., 2000, Biochemistry. 39 (8): 1935-41.
  3. Schmidt-Ott KM. et al., 2007, J Am Soc Nephrol. 18 (2): 407-13.

Sino Biological Inc. liefert LCN2 / NGAL Antikörper mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über LCN2 / NGAL Antikörper lesen Sie bitte: http://www.sinobiological.com/LCN2-NGAL-Antibody-g-9049.html

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