LC3A / MAP1LC3A Protein (His Tag)

15.03.2013

Sino Biological Inc. liefert LC3A / MAP1LC3A Protein (His Tag) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über LC3A / MAP1LC3A Protein (His Tag) lesen Sie bitte: http://www.sinobiological.com/LC3A-MAP1LC3A-Protein-g-10612.html

Produkt-Information von LC3A / MAP1LC3A Protein

Synonym	MAP1LC3A
Protein Construction	A DNA sequence encoding the mature form of human MAP1LC3A (Q9H492-1) (Met1-Phe121) was expressed with a polyhistide tag at the C-terminus.
Source	Human
Expression Host	E.coli

QC Testing von LC3A / MAP1LC3A Protein

Purity	> 95% as determined by SDS-PAGE	SDS-PAGE: LC3A protein
Endotoxin	Please contact us for more information.
Stability	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal	Met
Molecular Mass	The recombinant human MAP1LC3A consists of 127 amino acids and predicts a molecular mass of 15.1 KDa. It migrates as an approximately 17 KDa band in SDS-PAGE under reducing conditions.
Formulation	Lyophilized from sterile PBS, 10% glycerol, pH 7.5. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. Please contact us for any concerns or special requirements.

Usage Guide von LC3A / MAP1LC3A Protein

Storage	Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution	A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Beschreibung von LC3A / MAP1LC3A Protein

LC3A, also known as MAP1LC3A, is one of the light chain subunits that functions together with both MAP1A and/or MAP1B. MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. As a light chain subunit, MAP1LC3A has an important part in neuronal development and in maintaining the balance between neuronal plasticity and rigidity. MAP1LC3A is expressed as two alternatively spliced isoforms that are expressed in testis, brain, heart, liver and skeletal muscle, but are absent in thymus and peripheral blood leukocytes.

References

Snásel J. et al., 1997, Folia Biol. 42 (5): 227-30.
Wallin M. et al., 1990, J Gen Virol. 71 (9): 1985-91.
Schoenfeld TA. et al., 1989, J Neurosci. 9 (5): 1712-30.