Mein Blog umfasst die aktuellesten News, Forschungsleistung, neuesten Produkte und Service von Sino Biological Inc. und die aktuelle News von Life Sciences. Sie können sich hier wissenschaftlich informieren.Willkommen zu meinem Blog.Viel Spaß!
| Immunogen | Recombinant Human ITGA6 & ITGB1 Heterodimer protein (Catalog#CT013-H2508H) |
| Antibody Type | Rabbit Polyclonal Antibody ( Antibody Purification Platform ) |
| Ig Type | Rabbit IgG |
| Formulation | 0.2 μm filtered solution in PBS with 5% trehalose |
| Preparation | Produced in rabbits immunized with purified, recombinant Human ITGA6 & ITGB1 Heterodimer (rh ITGA6 & ITGB1 Heterodimer; Catalog#CT013-H2508H; P23229-3 & P05556-1; Met 1-Ser 1011, Met 1-Asp 728). Total IgG was purified by Protein A affinity chromatography. |
| Specificity | Human ITGA6 & ITGB1 Heterodimer |
| Western blot | This antibody can be used at 1-2 μg/mL with the appropriate secondary reagents to detect Human ITGA6 & ITGB1 Heterodimer in WB. Using a DAB detection system, the detection limit for Human ITGA6 & ITGB1 Heterodimer is approximately 8 ng/lane under non-reducing conditions and 16 ng/lane under reducing conditions. |
| Direct ELISA | This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect Human ITGA6 & ITGB1 Heterodimer. The detection limit for Human ITGA6 & ITGB1 Heterodimer is approximately 0.00975 ng/well. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. |
Integrin alpha-6, also known as CD49 antigen-like family member F, VLA-6, CD49f and ITGA6, is a single-pass type I membrane protein which belongs to theintegrin alpha chain family. It contains 7FG-GAP repeats. Integrin alpha-6 / beta-4 is predominantly expressed by epithelia. It is a receptor for laminin on platelets. Integrin alpha-6 / beta-4 is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome. Defects in ITGA6 are a cause of epidermolysis bullosa letalis with pyloric atresia (EB-PA). It is an autosomal recessive, frequently lethal, epidermolysis bullosa with variable involvement of skin, nails, mucosa, and with variable effects on the digestive system. Integrin beta-1, also known as Fibronectin receptor subunit beta, VLA-4 subunit beta, CD29 and ITGB1, is a single-pass type I membrane protein which belongs to theintegrin beta chain family. It contains oneVWFA domain. Integrin beta-1 / ITGB1 associates with either alpha-1, alpha-2, alpha-3, alpha-4, alpha-5, alpha-6, alpha-7, alpha-8, alpha-9, alpha-10, alpha-11 or alpha-V. It binds LGALS3BP and ITGB1BP3, when associated with alpha-7, but not with alpha-5. Integrin beta-1 / ITGB1 interacts with FLNA, FLNB and RANBP9. Integrin beta-1 / ITGB1 binds to human echoviruses 1 and 8 capsid proteins and acts as a receptor for these viruses. Integrins alpha-1 / beta-1, alpha-2 / beta-1, alpha-10 / beta-1 and alpha-11 / beta-1 are receptors for collagen. Integrins alpha-1 / beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G-E-R in collagen.Integrins alpha-2 / beta-1, alpha-3/beta-1, alpha-4 / beta-1, alpha-5 / beta-1, alpha-8 / beta-1, alpha-10/beta-1, alpha-11 / beta-1 and alpha-V / beta-1 are receptors for fibronectin. Integrin alpha-4 / beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin alpha-1 / beta-1, alpha-2 / beta-1, alpha-6 / beta-1 and alpha-7 / beta-1 are receptors for lamimin. Integrin alpha-4 / beta-1 is a receptor for VCAM1.
Sino Biological Inc. liefert ITGA6 & ITGB1 Heterodimer Antikörper mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.
Weitere Informationen über ITGA6 & ITGB1 Heterodimer Antikörper lesen Sie bitte: http:www.sinobiological.com/ITGA6-&-ITGB1-Heterodimer-Antibody-g-9282.html
/https%3A%2F%2Fassets.over-blog.com%2Ft%2Fcedistic%2Fcamera.png)