IL36G / IL1F9 (aa 18-169) Protein

05.09.2012

Produkt-Information von IL36G / IL1F9 Protein

Synonym	IL1E, IL36G, IL1H1, IL1RP2, IL1F9
Protein Construction	A DNA sequence encoding the human IL1F9 (NP_062564) (Ser18-Asp169) was expressed and purified, with two additional amino acids (Gly & Pro) at the N-terminus.
Source	Human
Expression Host	E.coli

IL36G / IL1F9 Protein QC Testing

Purity	> 96 % as determined by SDS-PAGE	SDS-PAGE: IL36G / IL1F9 protein
Endotoxin	Please contact us for more information.
Stability	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal	Gly
Molecular Mass	The recombinant human IL1F9 consists of 154 amino acids and predicts a molecular mass of 17 KDa. It migrates as an approximately 16 KDa band in SDS-PAGE under reducing conditions.
Formulation	Lyophilized from a 0.2μm filtered solution of PBS pH 7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.

Usage Guide von IL36G / IL1F9 Protein

Storage	Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution	A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

IL36G / IL1F9 Protein Description

IL-1F9, also known as IL-36G and interleukin 36, gamma, is a member of the interleukin-1 (IL-1) family of cytokines. Interleukin-1 (IL-1) has been implicated in neuroimmune responses and has pleiotropic actions in the brain. The activity of this cytokine is mediated by interleukin 1 receptor-like 2(IL1RL2 / IL1R-rp2) IL-1F9 has been found function in activating nuclear factor- Kappa B (NF-κB) through the orphan receptor IL-1 receptor-related protein 2 (IL1R-rp2) in Jurkat cells. IL-1F9 is expressed strongly in keratinocytes and its expression is induced in skin during contact hypersensitivity and in psoriasis patients. This cytokine is also constitutively expressed primarily in the placenta and the squamous epithelium of the esophagus. The three-dimensional folding of IL-1F9 is similar to that of IL-1Ra, therefore, IL-1F9 appears to be a possible IL-1 receptor antagonist rather than an agonist.

References

Dinarello CA. 2002, Clin Exp Rheumatol. 20 (5): S1-13.
Bergl f E. et al., 2003, J Neuroimmunol. 139 (1-2): 36-43.
Dunn E. et al., 2001, Trends Immunol. 22 (10): 533-6.
Towne JE. et al., 2004, J Biol Chem. 279 (14): 13677-88.

Sino Biological Inc. liefert IL36G / IL1F9 (aa 18-169) Protein mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über IL36G / IL1F9 (aa 18-169) Protein lesen Sie bitte: http://www.sinobiological.com/IL36G-IL1F9-Protein-g-9218.html

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat No
IL1F9	Human	IL36G / IL1F9 Protein, Recombinant, with Native	10124-HNAE
IL1F9	Human	IL36G / IL1F9 (aa 18-169) Protein, Recombinant	10124-H07E1
IL1F9	Human	IL36G / IL1F9 (aa 18-169) Protein, Recombinant	10124-HNCE1