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IL17RC Antikörper

Sino Biological Inc. liefert IL17RC Antikörper mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über IL17RC Antikörper lesen Sie bitte: http://www.sinobiological.com/IL17RC-Antibody-g-10157.html

Produkt-Information von IL17RC Antikörper

Immunogen

Recombinant Human IL17RC protein (Catalog#11747-H08B)

Antibody Type Rabbit Polyclonal Antibody ( Antibody Purification Platform )
Ig Type

Rabbit IgG

Formulation 0.2 μm filtered solution in PBS with 5% trehalose
Preparation

Produced in rabbits immunized with purified, recombinant Human IL17RC (rh IL17RC; Catalog#11747-H08B; NP_116121.2; Met 1-Ala 454). Total IgG was purified by Protein A affinity chromatography.

Usage Guide von IL17RC Antikörper

Specificity

Human IL17RC

Direct ELISA This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect Human IL17RC. The detection limit for Human IL17RC is approximately 0.00975 ng/well.
Storage This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Verwandte Produkte & Themen von IL17RC Antikörper

Related Areas:

Immunology>>Cytokine & Receptor>>Interleukin & Receptor>>IL-17 Family & IL-17 Receptor Family>>IL-17RC

Proteins:
Molecule Species Description //For Detailed Info. and Price------CLICK! Cat No
IL17RC Human IL17RC Protein, Recombinant 11747-H02H
IL17RC Human IL17RC (aa 1-454) Protein, Recombinant 11747-H08B
Antibodies:
Molecule Application Description //For Detailed Info. and Price------CLICK! Cat No
Human IL17RC ELISA IL17RC Antibody 11747-RP01
Human IL17RC ELISA IL17RC Antibody (Antigen Affinity Purified) 11747-RP02

Hintergrund von IL17RC Antikörper

Interleukin-17 receptor C (IL-17RC) is a single-pass transmembrane protein that shares similarity with the IL-17R. IL-17RC functions as a receptor for both IL-17A and IL-17F, both of which are considered as factors contributing to the progression of inflammatory and autoimmune diseases. IL-17A and IL-17F mediate inflammatory activities via the IL-17 receptor complex, comprised of the IL-17RA and IL-17RC subunits. Soluble version of IL-17RC should be an effective antagonist of IL-17A and IL-17F mediated inflammatory diseases. IL-17RC and IL-17RA have been found to be overexpressed in rheumatoid arthritis (RA) peripheral whole blood and their expression was detected locally in RA synovium. IL-17RC protein expression was significantly higher in androgen-independent prostate cancers than in androgen-dependent ones. This protein is differentially expressed in prostatic cells and cancer tissues and may play a negative or positive role in the initiation and progression of prostate cancer.

References

  1. Allen W. et al., 2010, Semin Immunopathol. 32 (1): 33-42.
  2. You ZB. et al., 2007, Neoplasia. 9 (6): 464-70.
  3. Zrioual S. et al., 2008, J Immunol. 180 (1):655-63.
  4. Kuestner RE. et al., 2010, J Immunol. 179 (8): 5462-73.

Primary Antibody Products

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