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| Immunogen | Recombinant Human IL13 / ALRH protein (Catalog#10369-H01H) |
| Antibody Type | Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform ) |
| Clone ID | 062 |
| Ig Type | Rabbit IgG |
| Formulation | 0.2 μm filtered solution in PBS with 5% trehalose |
| Preparation | This antibody was obtained from a rabbit immunized with purified, recombinant Human IL13 / ALRH (rh IL13 / ALRH; Catalog#10369-H01H; AAK53823.1; Gly 21-Asn 132). |
| Specificity | Human IL13 / ALRH |
| Has cross-reactivity in ELISA with Cynomolgus IL13 | |
| Western blot | This antibody can be used at 1-2 μg/mL with the appropriate secondary reagents to detect Human IL13 in WB. Using a DAB detection system, the detection limit for Human IL13 is approximately 2 ng/lane under non-reducing conditions and 1 ng/lane under reducing conditions. |
| Direct ELISA | This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human IL13. The detection limit for Human IL13 is approximately 0.0049 ng/well. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. |
Interleukin 13 (IL-13) is a single-chain cytokine which belongs to the IL13/IL4 family. In humans, IL13 is secreted by many cell types, but especially by T helper type 2 (Th2) cells. IL13 inhibits the production of pro-inflammatory cytokines and chemokines, and thus down-regulates macrophage activity. Meanwhile, IL-13 synergizes with IL2 in regulating IFN-gamma synthesis. IL-13 binds to a multi-subunit receptor comprising the alpha chain of the IL-4 receptor (IL-4Rα) and at least one of two known IL-13-specific binding chains (IL13 Rα1 and IL13 Rα2), and exerts its effects through signal transducer and activator of transcription 6 (STAT6), like IL-4. Accordingly, IL-13 may be critical in regulating inflammatory and immune responses as a central mediator in various cell types.
Sino Biological Inc. liefert IL13 / ALRH Antikörper mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.
Weitere Informationen über IL13 / ALRH Antikörper lesen Sie bitte: http:www.sinobiological.com/IL13-ALRH-Antibody-g-9193.html
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