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| Immunogen | Recombinant Human HIST1H3A / Histone H3.1 protein (Catalog#11231-HNAE) |
| Antibody Type | Mouse Monoclonal Antibody ( Mouse mAb Service Platform ) |
| Clone ID | 1F6D7C4 |
| Ig Type |
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| Formulation | 0.2 μm filtered solution in PBS with 5% trehalose |
| Preparation | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human HIST1H3A / Histone H3.1 (rh HIST1H3A / Histone H3.1; Catalog#11231-HNAE; P6843; Met 1-Ala 136). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Specificity | Human HIST1H3A / Histone H3.1 | |||
| Immunochemistry | IHC-P: 1-20 μg/mL
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| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃.Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. |
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| HIST1H3A | Human | HIST1H3A /Histone H3.1 Protein, Recombinant | 11231-HNAE |
| Molecule | Application | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| Human HIST1H3A | IHC-P | HIST1H3A / Histone H3.1 Antibody | 11231-MM01 |
Histone H3.1, also known as HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J, is a member of thehistone H3 family which is a core component of nucleosome. It is expressed during S phase, then expression strongly decreases as cell division slows down during the process of differentiation. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.
Sino Biological Inc. liefert HIST1H3A / Histone H3.1 Antikörper mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.
Weitere Informationen über HIST1H3A / Histone H3.1 Antikörper lesen Sie bitte: http://www.sinobiological.com/HIST1H3A-Histone-H3.1-Antibody-g-8775.html
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