GSTZ1 Protein (His Tag)

15.03.2013

Sino Biological Inc. liefert GSTZ1 Protein (His Tag) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über GSTZ1 Protein (His Tag) lesen Sie bitte: http://www.sinobiological.com/GSTZ1-Protein-g-10610.html

Produkt-Information von GSTZ1 Protein

Synonym :	GSTZ1, MAAI
Protein Construction:	A DNA sequence encoding the mature form of human GSTZ1 (NP_665877.1) (Met1-Ala216) was expressed with a polyhistide tag at the N-terminus.
Source:	Human
Expression Host:	E.coli

QC Testing von GSTZ1 Protein

Purity:	> 95% as determined by SDS-PAGE	SDS-PAGE: GSTZ1 protein
Endotoxin:	Please contact us for more information.
Stability:	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal:	His
Molecular Mass:	The recombinant human GSTZ1 consists of 231 amino acids and predicts a molecular mass of 26 KDa. It migrates as an approximately 27 KDa band in SDS-PAGE under reducing conditions.
Formulation:	Lyophilized from sterile PBS, 10% glycerol, PH7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. Please contact us for any concerns or special requirements.

Usage Guide von GSTZ1 Protein

Storage:	Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution:	A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Beschreibung von GSTZ1 Protein

GSTZ1 gene is a member of the glutathione S-transferase (GSTs) super-family which encodes multifunctional enzymes important in the detoxification of electrophilic molecules, including carcinogens, mutagens, and several therapeutic drugs, by conjugation with glutathione. GSTZ1 is a bifunctional protein which has minimal glutathione-conjugating activity with ethacrynic acid and 7-chloro-4-nitrobenz-2-oxa-1,3-diazole and maleylacetoacetate isomerase activity. GSTZ1 catalyzes the glutathione dependent oxygenation of dichloroacetic acid to glyoxylic acid. GSTZ1 participates in the catabolism of phenylalanine and tyrosine. Thus defects in GSTZ1 cause harsh metabolic disorders including alkaptonuria, phenylketonuria and tyrosinaemia.

References

Tong Z. et al., 1999, Chem Res Toxicol. 11 (11): 1332-8.
Tong Z. et al., 1999, Biochem J. 331 (2): 371-4.
Ketterer B. 2001, Chem Biol Interact. 138 (1): 27-42.