Fractalkine / CX3CL1 Antikörper

23.08.2012

Produkt-Information von Fractalkine / CX3CL1 Antikörper

Immunogen	Recombinant Human Fractalkine / CX3CL1 protein (Catalog#10636-H08H)
Antibody Type	Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform )
Clone ID	409
Ig Type	Rabbit IgG
Formulation	0.2 μm filtered solution in PBS with 5% trehalose
Preparation	This antibody was obtained from a rabbit immunized with purified, recombinant Human Fractalkine / CX3CL1 (rh Fractalkine / CX3CL1; Catalog#10636-H08H; NP_002987.1; Met 1-Arg 339).

Usage Guide von Fractalkine / CX3CL1 Antikörper

Specificity	Human Fractalkine / CX3CL1
Western blot	This antibody can be used at 1-2 μg/mL with the appropriate secondary reagents to detect Human CX3CL1 in WB. Using a DAB detection system, the detection limit for Human CX3CL1 is approximately 1 ng/lane under non-reducing conditions and 0.25 ng/lane under reducing conditions.
Direct ELISA	This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human CX3CL1. The detection limit for Human CX3CL1 is approximately 0.0049 ng/well.
Storage	This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Verwandte Produkte & Themen von Fractalkine / CX3CL1 Antikörper

Related Areas:

Cancer>>Angiogenesis>>Cytokines/Chemokines in Angiogenesis>>Fractalkine/CX3CL1

Immunology>>Cytokine & Receptor>>Chemokine & Receptor>>Fractalkine/CX3CL1

Proteins:

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
Fractalkine/CX3CL1	Human	Fractalkine/CX3CL1 Protein, Recombinant	10636-H08H

Antibodies:

Molecule	Application	Description //For Detailed Info. and Price------CLICK!	Cat. No
Human Fractalkine /CX3CL1	WB, ELISA	Mouse Monoclonal Antibody	10636-MM02
Human Fractalkine /CX3CL1	ELISA	Rabbit Polyclonal Antibody	10636-RP01
Human Fractalkine /CX3CL1	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)	10636-RP03
Human Fractalkine /CX3CL1	WB, ELISA	Fractalkine / CX3CL1 Antibody	10636-R409

Hintergrund von Fractalkine / CX3CL1 Antikörper

Chemokine (C-X3-C motif) ligand 1 (CX3CL1) is a large cytokine protein containing multiple domains and is the only known member of the CX3C chemokine family. It is also commonly known as fractalkine (in humans) and neurotactin (in mice). The polypeptide structure of CXC3L1 differs from the typical structure of other chemokines. Mature human CX3CL1 consists of a 76 aa residue chemokine domain, a 241 aa residue stalk region containing 17 degenerate mucin-like repeats, a 19 aa residue transmembrane segment and a 37 aa residue cytoplasmic domain. The extracellular domain of human CX3CL1 can be released, possibly by proteolysis at the dibasic cleavage site proximal to the membrane, to generate soluble CX3CL1. Soluble CX3CL1 potently chemoattracts T cells and monocytes, while the cell-bound CX3CL1 promotes strong adhesion of leukocytes to activated endothelial cells where it is primarily expressed. CX3CL1 elicits its adhesive and migratory functions by interacting with the chemokine receptor CX3CR1.

References

Bazan, J. F.,et al.,1997, Nature. 385: 640-644.
Imai,T. et al., 1997, Cell. 91: 521-530.
Nomiyama, H. et al., 1998, Cytogenet. Cell Genet. 81: 10-11.
Papadopoulos, E. et al., 1999, Eur. J. Immunol. 29 (8): 2551-2559.
Umehara, H. et al., 2004, Arterioscler. Thromb. Vasc. Biol. 24 (1): 34-40.

Sino Biological Inc. liefert Fractalkine / CX3CL1 Antikörper mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über Fractalkine / CX3CL1 Antikörper lesen Sie bitte: http://www.sinobiological.com/Fractalkine-CX3CL1-Antibody-g-9477.html