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Cystatin S / CST4 Antikörper

Produkt-Information von Cystatin S / CST4 Antikörper

Immunogen

Recombinant Human Cystatin S / CST4 protein (Catalog#11542-H08H)

Antibody Type Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform )

Clone ID

006

Ig Type

Rabbit IgG

Formulation 0.2 μm filtered solution in PBS with 5% trehalose
Preparation

This antibody was obtained from a rabbit immunized with purified, recombinant Human Cystatin S / CST4 (rh Cystatin S / CST4; Catalog#11542-H08H; NP_001890.1; Met 1-Ala 141).

Usage Guide von Cystatin S / CST4 Antikörper

Specificity

Human Cystatin S / CST4

Western blot This antibody can be used at 1-2 μg/mL with the appropriate secondary reagents to detect Human CST4 in WB.
Direct ELISA This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human CST4. The detection limit for Human CST4 is approximately 0.195 ng/well.
Storage This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Verwandte Produkte & Themen von Cystatin S / CST4 Antikörper

Related Areas:

Enzyme>>Protease & Regulator>>Cysteine Protease & Regulator>>Cystatin>>Cystatin S/CST4

Cancer>>Angiogenesis>>Cystatin>>Cystatin S/CST4

Proteins:
Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
Cystatin S/CST4 Human Cystatin S/CST4 Protein, Recombinant 11542-H08H
Antibodies:
Molecule Application Description //For Detailed Info. and Price------CLICK! Cat. No
Human
Cystatin S/CST4
WB, ELISA Cystatin S / CST4 Antibody 11542-MM01
Human
Cystatin S/CST4
WB, ELISA Cystatin S/CST4 Antibody, Rabbit PAb 11542-RP01
Human
Cystatin S/CST4
WB, ELISA Cystatin S/CST4 Antibody, Rabbit PAb (Antigen Affinity Purified) 11542-RP02
Human
Cystatin S/CST4
WB, ELISA Cystatin S / CST4 Antibody 11542-R006

Hintergrund von Cystatin S / CST4 Antikörper

Cystatin-S, also known as Cystatin-4, Salivary acidic protein 1, Cystatin-SA-III and CST4, is a secreted protein which belongs to thecystatin family. Cystatin-4 / CST4 is expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). It is also expressed in saliva, tears, urine and seminal fluid. The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. Cystatin-4 / CST4 strongly inhibits papain and ficin, partially inhibits stem bromelain and bovine cathepsin C, but does not inhibit porcine cathepsin B or clostripain. Papain is inhibited non-competitively. Cystatin-4 / CST4 is an S-type cystatin, based on its high level of expression in saliva, tears and seminal plasma. The specific role in these fluids is unclear but antibacterial and antiviral activity is present, consistent with a protective function.

References

  1. Saitoh,E. et al., 1992, Agents Actions Suppl. 38 (Pt 1): 340-8.
  2. Saitoh E, et al., 1992, Biomed Biochim Acta. 50 (4-6): 599-605.
  3. Baron A, et al., 2000, Oral diseases. 5 (3): 234-40.
  4. Dickinson, DP. et al., 2002, DNA Cell Biol. 21 (1): 47-65.

Sino Biological Inc. liefert Cystatin S / CST4 Antikörper mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über Cystatin S / CST4 Antikörper lesen Sie bitte: http://www.sinobiological.com/Cystatin-S-CST4-Antibody-g-9476.html

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