FLT3 / CD135 / FLK2 Antikörper ( FITC )

Sino Biological Inc. liefert FLT3 / CD135 / FLK2 Antikörper ( FITC ) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über FLT3 / CD135 / FLK2 Antikörper ( FITC ) lesen Sie bitte:http://www.sinobiological.com/FLT-3-CD135-FLK-2-Protein-Antibody-a-730.html

Produkt-Information von FLT3 / CD135 / FLK2 Antikörper

Usage Guide von FLT3 / CD135 / FLK2 Antikörper

Specificity	Human FLT3 / CD135 / FLK2
Flow Cytometry	Flow cytometric analysis of anti-human CD135 on human whole blood monocytes. The fluorescence histograms were derived from events with the forward and side light-scatter characteristics of viable monocytes. Flow cytometry was performed on a BD FACSCalibur flow cytometry system Please refer to www.sinobiological.com/Flow-Cytometry-FACS-Protocols-a-750.html for technical protocols.
Storage	This antibody is stable for 12 months from date of receipt when stored at 2℃-8℃. Protected from prolonged exposure to light. Do not freeze ! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.

Verwandte Produkte & Themen von FLT3 / CD135 / FLK2 Antikörper

Hintergrund von FLT3 / CD135 / FLK2 Antikörper

FL cytokine receptor, also known as tyrosine-protein kinase receptor FLT3, Stem cell tyrosine kinase 1, STK-1, FLT3 and CD135, is a single-pass type I membrane protein. CD135 belongs to theprotein kinase superfamily and the CSF-1/PDGF receptor subfamily. It contains oneIg-like C2-type domain and oneprotein kinase domain. CD135 is an important cell surface marker used to identify certain types of hematopoietic progenitors in thebone marrow. Specifically,multipotent progenitors (MPP) andcommon lymphoid progenitors (CLP) express surface CD135 at high levels. This marker is therefore used to differentiatehematopoietic stem cells (HSC), which are CD135 negative, from MPPs, which are CD135 positive. Signaling through CD135 plays a role in cell survival, proliferation, and differentiation. CD135 is also important forlymphocyte (B cellandT cell) development, but not for the development of other blood cells (myeloiddevelopment). Identified as a proto-oncogene, the mutations of FLTS gene are associated with certain carcinomas.

References

1. Reilly, JT. et al.,2003, Leuk. Lymphoma. 44 (1): 1-7.
2. Marcucci, G. et al., 2005, Curr. Opin. Hematol.12 (1): 68-75.
3. Sternberg, DW. et al.,2005, Curr. Opin. Hematol.12 (1): 7-13.
4. Stubbs, MC. et al., 2007, Current drug targets. 8 (6): 703-14.

Primary Antikörper von Sino Biological Inc.