Fibronectin Fragment 2 Antikörper

06.01.2012

Produkt-Information von Fibronectin Fragment 2 Antikörper

Immunogen	Recombinant human Fibronectin Fragment 2 protein ( Catalog#10314-H08H )
Antibody Type	Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform )
Clone ID	014
Ig Type	Rabbit IgG
Formulation	0.2 μm filtered solution in PBS with 5% trehalose
Preparation	This antibody was obtained from a rabbit immunized with purified, human cell-derived, recombinant human Fibronectin Fragment 2 ( Catalog#10314-H08H ; Ser 607 - Pro 1265 ; CAD91166 ).

Usage Guide von Fibronectin Fragment 2 Antikörper

Specificity	Human Fibronectin Fragment 2
Western blot	This antibody can be used at 1 - 2 μg/mL with the appropriate secondary reagents to detect human Fibronectin Fragment 2 in WB. Using a DAB detection system, the detection limit for human Fibronectin Fragment 2 is approximately 0.5 ng/lane under non-reducing conditions and 0.25 ng/lane under reducing conditions
Direct ELISA	This antibody can be used at 0.1 - 0.2 μg/mL with the appropriate secondary reagents to detect human Fibronectin Fragment 2. The detection limit for human Fibronectin Fragment 2 is approximately 0.00245 ng/well
Storage	This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃.Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Verwandte Produkte & Themen von Fibronectin Fragment 2 Antikörper

Related Areas:

Stem Cell>>Mesenchymal Stem Cell (MSC)>>Osteoblast & Osteoclast Marker>>Fibronectin/FN1

Stem Cell>>Mesenchymal Stem Cell (MSC)>>Mesenchymal Stem Cell Marker>>Fibronectin/FN1

Cancer>>Angiogenesis>>ECM Molecules in Angiogenesis>>Fibronectin/FN1

Immunology>>Innate Immunity>>Coagulation>>Fibronectin/FN1

Immunology>>Adhesion Molecule>>Extracellular Matrix Molecule>>Extracellular Matrix Protein>>Fibronectin/FN1

Proteins:

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
Fibronectin/FN1	Human	Fibronectin Fragment 2 Protein, Recombinant	10314-H08H

Antibodies:

Molecule	Application	Description //For Detailed Info. and Price------CLICK!	Cat. No
Human Fibronectin/FN1	WB, ELISA	Mouse Monoclonal Antibody	10314-MM02
Human Fibronectin/FN1	WB, ELISA	Fibronectin/FN1 Antibody, Rabbit MAb	10314-R014
Human Fibronectin/FN1	ELISA	Rabbit Polyclonal Antibody	10314-RP01
Human Fibronectin/FN1	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)	10314-RP03

Hintergrund von Fibronectin Fragment 2 Antikörper

Fibronectin ( FN ) is a large glycoprotein present as soluble disulfide-linked dimeric form in plasma and body fluids, and as dimeric or multimeric form at the cell surface or in extracellular matrix ( ECM ). Each monomer of FN consists of three types of homologous repeating units, that is 12 type I repeats, two type II repeats and 15-17 type III repeats. The occurrence of multiple isoforms results from alternative mRNA splicing of the ED-A, ED-B and III-CS regions, and subsequent post-translational modification. As an ECM component and one of the primary cell adhesion molecules, Fibronectin can be a ligand for fibrin, heparin, chondroitin sulfate, collagen/gelatin, as well as many integrin receptors through which FN mediates the variety of cellular signaling pathways. Accordingly, Fibronectin is involved in cell adhesion and migration, growth and differentiation, morphogenesis, wound healing, blood coagulation, host defense, and metastasis. Conversion of the non-functional soluble fibronectin to fibronectin fibrils requires conformational changes and exposure of cryptic epitopes necessary for polymerization. The fragment 2 of FN comprises the first 7 FN type III repeats and is suggested to be important for self association.

References

Magnus, K. et al., 1998, Arterioscler. Thromb. Vasc. Biol. 18: 1363-70.
Sechler, J.L. et al., 2001, J. Cell Biol. 154:1081-8.
Williams, C.M. et al., 2008, Cancer. Res. 68:3185-92.
Rounmen, P. et al., 2002, J. Cell. Sci. 115: 3861-3.

Sino Biological Inc. liefert Fibronectin Fragment 2 Antikörper mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über Fibronectin Fragment 2 Antikörper lesen Sie bitte: http://www.sinobiological.com/Fibronectin-Antibody-g-6046.html