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Decorin / DCN / SLRR1B Antikörper

Produkt-Informatin von Decorin / DCN / SLRR1B Antikörper

Immunogen

Recombinant human Decorin protein ( Catalog#10189-H08H )

Antibody Type Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform )

Clone ID 

004

Ig Type

Rabbit IgG

Formulation 0.2 μm filtered solution in PBS with 5% trehalose
Preparation

This antibody was obtained from a rabbit immunized with purified, human cell-derived, recombinant human Decorin ( rh Decorin ; Catalog#10189-H08H ; NP_001911.1 ; Met 1 - Lys 359 ).

Usage Guide von Decorin / DCN / SLRR1B Antikörper

Specificity

Human Decorin / DCN / SLRR1B

Western blot This antibody can be used at 1 - 2 μg/mL with the appropriate secondary reagents to detect human Decorin in WB. Using a DAB detection system, the detection limit for human Decorin is approximately 1 ng/lane under non-reducing conditions and 0.5ng/lane under reducing conditions
Direct ELISA This antibody can be used at 0.1 - 0.2 μg/mL with the appropriate secondary reagents to detect human Decorin. The detection limit for human Decorin is approximately  0.0049 ng/well
Storage This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃.Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Verwandte Produkte & Themen von Decorin / DCN / SLRR1B Antikörper

Related Areas:

Stem Cell>>Mesenchymal Stem Cell (MSC)>>Osteoblast & Osteoclast Marker>>Decorin

Cancer>>Cancer Stem Cell (CSC)>>Decorin

Cancer>>Angiogenesis>>ECM Molecules in Angiogenesis>>Decorin

Cancer>>Growth Factor & Receptor>>TGF-beta Superfamily>>TGF-beta Family>>Decorin

Immunology>>Adhesion Molecule>>Extracellular Matrix Molecule>>Proteoglycan>>Decorin

Immunology>>Cytokine & Receptor>>TGF-beta Superfamily>> TGF-beta Superfamily Modulators>>Decorin

Proteins:
Decorin Protein, Recombinant
Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
Decorin Human Decorin/Fc Protein, Recombinant 10189-H01H
Decorin Human Decorin Protein, Recombinant 10189-H08H
Antibodies:
Molecule Application Description //For Detailed Info. and Price------CLICK! Cat. No
Human 
Decorin
WB, ELISA Decorin Antibody, Rabbit MAb 10189-R004
Human 
Decorin
WB, ELISA Decorin Antibody, Rabbit PAb 10189-RP01
Human 
Decorin
WB, ELISA Decorin Antibody, Rabbit PAb (Antigen Affinity Purified) 10189-RP02

Decorin / DCN / SLRR1B Antikörper

Decorin is a ubiquitous small cellular or pericellular matrix proteoglycan and is closely related in structure to biglycan protein. It belongs to the small leucine-rich proteoglycan (SLRP) family and consists of a core protein and a covalently linked glycosaminoglycan chain which is either chondroitin sulfate (CS) or dermatan sulfate (DS). As a component of connective tissue, decorin interacts with several extracellular matrix components, such as type I collagen and fibronectin, and plays a role in matrix assembly. The decorin core protein also binds to growth factors including TGF-beta, and to the decorin endocytosis receptor. Decorin is capable of suppressing the growth and the metastasis of a wide range of cancer cells in vitro through attenuation of the EGFR -mediated intacellular signaling and induction of apoptosis. Multiple alternatively spliced transcript variants for the decorin gene have been described. Mutations or deficiency of the decorin gene are associated with Marfan syndrome.

References

  1. Pulkkinen, L. et al., 1990, J. Biol. Chem. 265: 17780-17785.
  2. Dugan, T.A. et al., 2006, J. Biol. Chem. 281: 38208-38216.
  3. Zafirpoulos, A. et al., 2008, Connect. Tissue. Res. 49: 244-248.
  4. Li, X. e t al., 2008, Blood. 112: 159-168.
  5. Krumdieck, R. et al., 1992, J. Immunol. 149: 3695-3701.

Sino Biological Inc. liefert Decorin / DCN / SLRR1B Antikörper mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über Decorin / DCN / SLRR1B Antikörper lesen Sie bitte: http://www.sinobiological.com/Decorin-Antibobdy-g-6045.html

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