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| Immunogen | Recombinant Human F13B / Coagulation factor XIII B chain protein (Catalog#11510-H08H) |
| Antibody Type | Rabbit Polyclonal Antibody ( Antibody Purification Platform ) |
| Ig Type | Rabbit IgG |
| Formulation | 0.2 μm filtered solution in PBS with 5% trehalose |
| Preparation | Produced in rabbits immunized with purified, recombinant Human F13B / Coagulation factor XIII B chain (rh F13B / Coagulation factor XIII B chain; Catalog#11510-H08H; P05160; Met 1-Thr 661). Total IgG was purified by Protein A affinity chromatography. |
| Specificity | Human F13B / Coagulation factor XIII B chain |
| Western blot | This antibody can be used at 1-2 μg/mL with the appropriate secondary reagents to detect Human F13B in WB. Using a DAB detection system, the detection limit for Human F13B is approximately 0.5 ng/lane under non-reducing conditions and 2 ng/lane under reducing conditions. |
| Direct ELISA | This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect Human F13B. The detection limit for Human F13B is approximately 0.00245 ng/well. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. |
Enzyme>>Protease & Regulator>>Serine Protease & Regulator>>Coagulation Factor XIII B chain
Immunology>>Innate Immunity>>Coagulation>>Coagulation Factor XIII B chain
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| Coagulation Factor XIII B chain | Human | Coagulation factor XIII B chain Protein, Recombinant | 11510-H08H |
| Molecule | Application | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| Human Coagulation Factor XIII B chain | WB, ELISA | F13B / Coagulation factor XIII B chain Antibody | 11510-RP01 |
Coagulation factor XIII B chain, also known as Fibrin-stabilizing factor B subunit, Protein-glutamine gamma-glutamyltransferase B chain, Transglutaminase B chain and F13B, is a secreted protein which contains 10 Sushi (CCP / SCR) domains. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as a plasma carrier molecules. Platelet factor XIII is composed of just 2 A subunits, which are identical to those of plasma origin. The B chain of factor XIII is not catalytically active, but is thought to stabilize the A subunits and regulate the rate of transglutaminase formation by thrombin. Factor XIII acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot. Factor XIII deficiency is classified into two categories: type I deficiency, characterized by the lack of both the A and B subunits; and type II deficiency, characterized by the lack of the A subunit alone. These defects can result in a lifelong bleeding tendency, defective wound healing, and habitual abortion. Defects in F13B are the cause of factor XIII subunit B deficiency (FA13BD) which is an autosomal recessive disorder characterized by a life-long bleeding tendency, impaired wound healing and spontaneous abortion in affected women.
Sino Biological Inc. liefert F13B / Coagulation factor XIII B chain Antikörper mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.
Weitere Informationen über F13B / Coagulation factor XIII B chain Antikörper lesen Sie bitte: http:www.sinobiological.com/F13B-Coagulation-factor-XIII-B-chain-Antibody-g-9276.html
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