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Epcr / PROCR Antikörper

Produkt-Information von Epcr / PROCR Antikörper

Immunogen

Recombinant Mouse Epcr / PROCR protein (Catalog#50874-M08H)

Antibody Type Rabbit Polyclonal Antibody ( Antibody Purification Platform )
Ig Type

Rabbit IgG

Formulation 0.2 μm filtered solution in PBS with 5% trehalose
Preparation

Produced in rabbits immunized with purified, recombinant Mouse Epcr / PROCR (rM Epcr / PROCR; Catalog#50874-M08H; Q64695; Met 1-Ser 214). Total IgG was purified by Protein A affinity chromatography.

Usage Guide von Epcr / PROCR Antibody

Specificity

Mouse Epcr / PROCR

Western blot This antibody can be used at 1-2 μg/mL with the appropriate secondary reagents to detect Mouse PROCR in WB. Using a DAB detection system, the detection limit for Mouse PROCR is approximately 0.5 ng/lane under non-reducing conditions and reducing conditions.
Direct ELISA This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect Mouse PROCR. The detection limit for Mouse PROCR is approximately 0.00975 ng/well.
Storage This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Verwandte Produkte & Themen von Epcr / PROCR Antikörper

Related Areas:

Immunology>>Innate Immunity>>Coagulation>>PROCR

Cardiovascular>>Coagulation>>PROCR

Proteins:
Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
PROCR Human Epcr / PROCR Protein, Recombinant 13320-H08H
PROCR Mouse Epcr / PROCR Protein, Recombinant 50874-M02H
PROCR Mouse EPCR / PROCR Protein, Recombinant 50874-M08H
Antibodies:
Molecule Application Description //For Detailed Info. and Price------CLICK! Cat. No
Mouse PROCR WB, ELISA Epcr / PROCR Antibody 50874-RP01

Hintergrund von Epcr / PROCR Antikörper

Endothelial protein C receptor (EPCR), also known as activated protein C receptor (APC receptor) or PROCR, is a receptor for Protein C. Protein C plays an important role in many metabolism processes in humans and other animals after activated by binding to Endothelial protein C receptor (EPCR). Because of the EPCR is found primarily on endothelial cells (cells on the inside of blood vessels), activated protein C is found maily near endothelial cells. Protein C is pleiotropic, with two main functions: anticoagulation and cytoprotection. Which function will be performed depend on whether or not protein C remains bind to EPCR after activated. The anticoagulation occur when it does not. When still bound to EPCR, activated protein C performs its cytoprotective effects.

References

  1. Nicolaes GA. et al., 2003, Semin Vasc Med. 3 (1): 33-46.
  2. Esmon CT. 2003, Chest 124 (3): 26-32.
  3. Mosnier LO. et al., 2007, Blood. 109: 3161-3172.

Sino Biological Inc. liefert Epcr / PROCR Antikörper mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über Epcr / PROCR Antikörper lesen Sie bitte: http:www.sinobiological.com/Epcr-PROCR-Antibody-g-9271.html

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