DYDC2 Protein (GST Tag)

10.10.2012

Produkt-Information von DYDC2 Protein

Synonym	DYDC2
Protein Construction	A DNA sequence encoding the mature form of human DYDC2 (Q96IM9) (Thr102-Pro176) was fused with the GST tag at the N-terminus.
Source	Human
Expression Host	E.coli

QC Testing von DYDC2 Protein

Purity	> 93 % as determined by SDS-PAGE	SDS-PAGE: DYDC2 protein
Endotoxin	Please contact us for more information.
Stability	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal	Met
Molecular Mass	The recombinant human DYDC2 /GST chimera consists of 307 amino acids and has a predicted molecular mass of 35.5 kDa. It migrates as an approximately 37 KDa band in SDS-PAGE under reducing conditions.
Formulation	Lyophilized from a 0.2μm filtered solution of PBS, pH7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.

Usage Guide von DYDC2 Protein

Storage	Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution	A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Beschreibung von DYDC2 Protein

DPY30 domain containing 2 is a member of the dpy-30 family. Members of this family act as determinants of male fertility and interaction partners of metal-responsive transcription factor 1 (MTF-1) in Drosophila. MTF-1 binds to metal response elements (MREs) and plays a key role in transition metal detoxification and homeostasis. Dpy-30 is the founding member of a protein family involved in chromatin modifications, notably histone methylation. Mutants affect mating type in yeast and male mating in C. elegans. As part of the MLL1/MLL complex, DPY30 domain containing 2 is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. DPY30 domain containing 2 may also play an indirect or direct role in endosomal transport.

References

Deloukas P. et al., 2004, Nature. 429 (6990): 375-81.
Rual JF. et al., 2005, Nature. 437 (7062): 1173-8.
Xin X. et al., 2009, Genome Res. 19 (7): 1262-9.

Sino Biological Inc. liefert DYDC2 Protein (GST Tag) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

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