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CNTN5 / Contactin-5 Antikörper

Produkt-Information von Contactin-5 / CNTN5 Antikörper

Immunogen

Recombinant human CNTN5 protein ( Catalog#10513-H08H )

Antibody Type Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform )

Clone ID 

121

Ig Type

Rabbit IgG

Formulation 0.2 μm filtered solution in PBS with 5% trehalose
Preparation

This antibody was obtained from a rabbit immunized with purified, human cell-derived, recombinant human CNTN5 / Contactin-5 ( rh CNTN5; Catalog#10513-H08H ; Met 1 - Gln 1059 ; NP_055176.1 ).

Usage Guide von Contactin-5 / CNTN5 Antikörper

Specificity

Human CNTN5 / Contactin-5

 

No cross-reactivity in ELISA with

Human Contactin-2 / CNTN2 / TAG-1

Human CNTN3 / Contactin-3 / BIG-1

Western blot This antibody can be used at 1 - 2 μg/mL with the appropriate secondary reagents to detect human CNTN5  in WB. Using a DAB detection system, the detection limit for human CNTN5 is approximately 0.5 ng/lane under non-reducing conditions. Use of this antibody under reducing conditions is not recommended
Direct ELISA This antibody can be used at 0.1 - 0.2 μg/mL with the appropriate secondary reagents to detect human CNTN5. The detection limit for human CNTN5 is approximately 0.00245 ng/well
Storage This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃.Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Verwandte Produkte & Themen von Contactin-5 / CNTN5 Antikörper

Related Areas:

Immunology>>Adhesion Molecule>> Cell Adhesion Molecule (IgSF CAM) >>Contactin 5/CNTN5

Proteins:
Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
Contactin 5/CNTN5/NB-2 Human Contactin 5/CNTN5 Protein, Recombinant 10513-H08H
Antibodies:
Molecule Application Description //For Detailed Info. and Price------CLICK! Cat. No
Human 
Contactin 5/CNTN5/NB-2
WB, ELISA Mouse Monoclonal Antibody 10513-MM02
Human 
Contactin 5/CNTN5/NB-2
ELISA Mouse Monoclonal Antibody 10513-MM11
Human 
Contactin 5/CNTN5/NB-2
WB, ELISA Contactin 5/CNTN5/NB-2 Antibody, Rabbit MAb 10513-R121
Human 
Contactin 5/CNTN5/NB-2
WB, ELISA Rabbit Polyclonal Antibody 10513-RP01
Human 
Contactin 5/CNTN5/NB-2
WB, ELISA Rabbit Polyclonal Antibody (Antigen Affinity Purified) 10513-RP02

Hintergrund von Contactin-5 / CNTN5 Antikörper

Human Contactin-5 ( CNTN5 ), also known as NB-2, is an membrane-anchored neuronal protein and also an adhesion molecule. CNTN5 is one of the neural recognition molecules in the contactin subgroup, which belongs to the immunoglobulin superfamily. CNTN5 shared 46, 43, 55 and 55% identities with CNTN1, CNTN2, CNTN3, CNTN4 respectively at the amino acid sequence level. Expression of NB-2 mRNA was restricted to cerebrum, cerebellum and was hardlty detectable, if any, in spinal cord. In humans, two isoforms have been identified. The long isoform of human NB-2 consists of 1100 amino acids residues and the short isoform lacks 74 amino acid residues between residues 19 and 93 of the long isoform. CNTN5 may play a role in the developing nervous system. NB-2 promoted neurite outgrowth of the cerebral cortical neurons but not the hippocampal neurons. CNTN5-deficient mice demonstrate impaired neuronal activity in the auditory system, suggesting that it plays specific roles in the development and/or maturation of the regions.

References

  1. Soumya R, et al., 2009, PLoS Genetics, Volume 5, Issue 6: e1000534
  2. Yoshimasa Kamei, et al., 2000, Genomics 69: 113-119.
  3. Junko O, et al., 1996, Neuroscience Letters, 218: 173-176.
  4. Junko O, et al., 2001, Journal of Neuroscience Research, 65:100-110.
  5. P. S. Walmod, et al., 2007, Handbook of Neurochemistry and Molecular Neurobiology.

Sino Biological Inc. liefert CNTN5 / Contactin-5 Antikörper mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über CNTN5 / Contactin-5 Antikörper lesen Sie bitte: http://www.sinobiological.com/Contactin-5-CNTN5-Antibody-g-6043.html

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