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Sino Biological Inc. liefert CD34 Antikörper mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.
Weitere Informationen über CD34 Antikörper lesen Sie bitte: http://www.sinobiological.com/CD34-Antibody-g-10095.html
| Immunogen | Recombinant Human CD34 protein (Catalog#10103-H08H) |
| Antibody Type | Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform ) |
| Clone ID | 009 |
| Ig Type | Rabbit IgG |
| Formulation | 0.2 μm filtered solution in PBS with 5% trehalose |
| Preparation | This antibody was obtained from a rabbit immunized with purified, recombinant Human CD34 (rh CD34; Catalog#10103-H08H; NP_001020280.1; Met 1-Thr 290). |
| Specificity | Human CD34 |
| Direct ELISA | This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human CD34. The detection limit for Human CD34 is approximately 0.625 ng/well. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. |
CD34 molecule is a member of a family of single-pass transmembrane sialomucin proteins, and is selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues. CD34 is highly glycosylated with nine potential N-linked and numerous potential O-linked glycosylation sites in its extracellular domain. Although used clinically in hematopoietic stem cell transplantation for more than 15 years, little is known about the exact function of CD34. It may act as an adhesion molecule in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells, and is also required for T cells to enter lymph nodes via interaction with L-selectin. It was indicated that CD34 is a phosphorylation target for activated PKC, and couples to the hematopoietic adapter protein CrkL, which were involved in CD34 signaling pathways. CD34 is abberantly expressed in many kinds of tumors and is implicated in leukemogenesis.
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