CD2 Antikörper

24.08.2012

Produkt-Information von CD2 Antikörper

Immunogen	Recombinant Mouse CD2 protein (Catalog#50537-M08H)
Antibody Type	Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform )
Clone ID	029
Ig Type	Rabbit IgG
Formulation	0.2 μm filtered solution in PBS with 5% trehalose
Preparation	This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD2 (rM CD2; Catalog#50537-M08H; NP_038514.1; Met 1-Ser 203).

Usage Guide von CD2 Antikörper

Specificity	Mouse CD2
Western blot	This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Mouse CD2 in WB.
Direct ELISA	This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Mouse CD2. The detection limit for Mouse CD2 is approximately 0.00975 ng/well.
Storage	This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Verwandte Produkte & Themen von CD2 Antikörper

Related Areas:

Cancer>>Cancer Stem Cell (CSC)>>CD2

Immunology>>Adaptive Immunity>>T Cell>>T Cell Migration/Adhesion>>CD2

Immunology>>Adaptive Immunity>>Costimulation & Costimulatory Molecule>>CD2

Immunology>>Cluster of Differentiation>>T Cell CD Antigen>>T Cell Migration/Adhesion>>CD2

Immunology>>Cluster of Differentiation>>Natural Killer (NK) Cell CD Antigen>>CD2

Proteins:

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
CD2	Human	CD2 Protein, Recombinant	10982-H08H
CD2	Mouse	CD2 Protein, Recombinant	50537-M08H
CD2	Rat	CD2 Protein, Recombinant	80158-R02H

Antibodies:

Molecule	Application	Description //For Detailed Info. and Price------CLICK!	Cat. No
Human CD2	WB, ELISA	CD2 Antibody (Antigen Affinity Purified)	10982-RP02
Human CD2	WB, ELISA	CD2 Antibody, Mouse MAb	10982-MM06
Mouse CD2	WB, ELISA	CD2 Antibody, Rabbit PAb	50537-RP01
Mouse CD2	WB, ELISA	CD2 Antibody, Rabbit PAb (Antigen Affinity Purified)	50537-RP02
Mouse CD2	WB, ELISA	CD2 Antibody	50537-R029

Hintergrund von CD2 Antikörper

T-cell surface antigen CD2, also known as T-cell surface antigen T11/Leu-5, Erythrocyte receptor, Rosette receptor, CD2 and SRBC, is a single-pass type I membrane protein. CD2 contains oneIg-like C2-type (immunoglobulin-like) domain and oneIg-like V-type (immunoglobulin-like) domain. CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48 / BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function. The CD2 family of receptors is evolutionarily conserved and widely expressed on cells within the hematopoietic compartment. CD2 family members regulate natural killer (NK) cell lytic activity and inflammatory cytokine production when engaged by ligands on tumor cells. The complex of CD2 and CD58 plays an important role in enhancing the adhesion of T lymphocytes to target cells, and promoting hyperplasia and activation of T lymphocytes. The expression of CD2 significantly increased with the severity of chronic HBV infection, which suggested that CD2 might contribute to the hepatocyte damage in chronic HBV infection.

References

Moingeon, P. et al., 1989, Immunol Rev111: 111-44.
Keogh, MC. et al., 1997, Immunol Cell Biol. 75 (4): 333-9.
McNerney, ME. et al., 2006, Curr Top Microbiol Immunol. 298:91-120.
Li,J. et al., 2008, Cell Mol Immunol5 (1): 69-73.

Sino Biological Inc. liefert CD2 Antikörper mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über CD2 Antikörper lesen Sie bitte: http://www.sinobiological.com/CD2-Antibody-g-9485.html