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| Immunogen | Recombinant Human CCL17 / TARC protein (Catalog#10233-HNAB) |
| Antibody Type | Mouse Monoclonal Antibody ( Mouse mAb Service Platform ) |
| Clone ID | 5C8C9 |
| Ig Type | Mouse IgG1 |
| Formulation | 0.2 μm filtered solution in PBS with 5% trehalose |
| Preparation | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CCL17 / TARC (rh CCL17 / TARC; Catalog#10233-HNAB; Q92583-1; Met 1-Ser 94). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Specificity | Human CCL17 / TARC |
| No cross-reactivity in WB and ELISA with Insectcell lysate | |
| Western blot | This antibody can be used at 1-2 μg/mL with the appropriate secondary reagents to detect Human CCL17 in WB. Using a DAB detection system, the detection limit for Human CCL17 is approximately 2 ng/lane under non-reducing conditions and not recommended under reducing conditions. |
| Direct ELISA | This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect Human CCL17. The detection limit for Human CCL17 is approximately 0.3125 ng/well. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. |
Immunology>>Cytokine & Receptor>>Chemokine & Receptor>>CCL17/TARC
Immunology>>Innate Immunity>>Monocyte/Macrophage>>Macrophage Marker>>CCL17/TARC
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| CCL17/TARC | Human | CCL17/TARC Protein, Recombinant | 10233-H08B |
| CCL17/TARC | Human | CCL17/TARC Protein, Recombinant, Native | 10233-HNAB |
| CCL17/TARC | Mouse | CCL17 / TARC Protein, Recombinant | 50046-MNAB |
| Molecule | Application | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| Human CCL17/TARC | WB, ELISA | 10233-MM03 |
C-C motif chemokine 17, also known as CC chemokine TARC, Small-inducible cytokine A17, Thymus and activation-regulated chemokine, CCL17 and SCYA17, is a secreted protein which belongs to the intercrine beta (chemokine CC) family. Chemokines are known to regulate the steady-state and inflammatory migration of cutaneous dendritic cells (DCs). The beta-chemokine CCL17, a ligand of CCR4, is inducibly expressed in a subset of DCs and is strongly up-regulated in atopic diseases. CCL17 / SCYA17 is constitutively expressed in the thymus and is produced by dendritic cells (DC), endothelial cells, keratinocytes (KC) and fibroblasts. CCL17 / SCYA17 is expressed at high levels in thymus and at low levels in the lung, colon and small intestine. CCL17 / SCYA17 is a chemotactic factor for T-lymphocytes but not monocytes or granulocytes. It may play a role in T-cell development in thymus and in trafficking and activation of mature T-cells. CCL17 / SCYA17 binds to CCR4.Chemokine receptor CCR4 and its ligands (CCL17 and CCL22) are important for the recruitment of memory T cells into the skin in various cutaneous immune diseases.
Sino Biological Inc. liefert CCL17 / TARC Antikörper mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.
Weitere Informationen über CCL17 / TARC Antikörper lesen Sie bitte: http://www.sinobiological.com/CCL17-TARC-Antibody-g-9082.html
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