AMIGO2 Protein (His Tag)

22.03.2013

Sino Biological Inc. liefert AMIGO2 Protein (His Tag) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über AMIGO2 Protein (His Tag) lesen Sie bitte: http://www.sinobiological.com/AMIGO2-AMIGO-2-alivin-1-Protein-Antibody-a-5734.html

Produkt-Information von AMIGO2 Protein

Synonym	AMIGO2, ALI1
Protein Construction	A DNA sequence encoding the human AMIGO2 (NP_862830.1) (Met1-Thr398) was expressed with a polyhistidine tag at the C-terminus.
Source	Human
Expression Host	Human Cells

QC Testing von AMIGO2 Protein

Purity	> 95 % as determined by SDS-PAGE	SDS-PAGE: AMIGO2 protein
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method
Stability	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal	Val 40
Molecular Mass	The recombinant human AMIGO2 consists of 370 amino acids and predicts a molecular mass of 42.3 KDa. It migrates as an approximately 58-63 KDa band in SDS-PAGE under reducing conditions.
Formulation	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. Please contact us for any concerns or special requirements.

Usage Guide von AMIGO2 Protein

Storage	Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution	A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Beschreibung von AMIGO2 Protein

AMIGO2 contains Ig-like C2-type (immunoglobulin-like) domain, 6 LRR (leucine-rich) repeats, 1 LRRCT domain and 1 LRRNT domain. It is a member of the immunoglobulin superfamily, AMIGO family. AMIGO2 may mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. It is required for depolarization-dependent survival of cultured cerebellar granule neurons. AMIGO2 is highly expressed in breast, ovary, cervix, and uterus. AMIGO2 may also contribute to signal transduction through its intracellular domain. It may play a role in the tumorigenesis of a subset of gastric adenocarcinomas.

References

Rouhiainen A. et al., 2003, J Cell Biol. 160: 963-73.
Kikkawa Y. et al., 2003, J Neurosci. 23: 5887-96.
Bassi R. et al., 2004, Oncogene. 23: 5056-67.