Alpha-2-glycoprotein / AZGP1 Protein (His Tag)

12.12.2012

Sino Biological Inc. liefert Alpha-2-glycoprotein / AZGP1 Protein (His Tag) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über Alpha-2-glycoprotein / AZGP1 Protein (His Tag) lesen Sie bitte: http://www.sinobiological.com/Alpha-2-glycoprotein-AZGP1-Protein-g-9987.html

Produkt-Information von Alpha-2-glycoprotein / AZGP1 Protein

Synonym	AZGP1, ZAG, ZNGP1
Protein Construction	A DNA sequence encoding the human AZGP1 (P25311) (Met1-Ser298) with a C-terminal polyhistidine tag was expressed.
Source	Human
Expression Host	Human Cells

QC Testing von Alpha-2-glycoprotein / AZGP1 Protein

Purity	> 95 % as determined by SDS-PAGE	SDS-PAGE: AZGP1 protein
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method
Stability	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal	Gln 21
Molecular Mass	The recombinant human AZGP1 comprises 289 amino acids and has a predicted molecular mass of 33.6 kDa. The apparent molecular mass of the protein is approximately 41 kDa in SDS-PAGE under reducing conditions.
Formulation	Lyophilized from sterile PBS, pH7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.

Usage Guide von Alpha-2-glycoprotein / AZGP1 Protein

Storage	Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution	A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Beschreibung von Alpha-2-glycoprotein / AZGP1 Protein

Alpha-2-glycoprotein, also known as AZGP1, is a member of the MHC class I family. It has been identified as a novel adipokine since is produced by both white and brown fat adipocytes and may act in a local autocrine fashion in the reduction of adiposity in cachexia. Alpha-2-glycoprotein can be detected in body fluids such as serum, sweat, and seminal and breast cyst fluids. It has been shown that alpha-2-glycoprotein can stimulate lipolysis by adipocytes in vivo and in vitro. Thus it is believed that alpha-2-glycoprotein plays an important role in the regulation of body weight, and age-dependent changes in genetically influenced obesity, and it also regulates melanin production by normal and malignant melanocytes. Alpha-2-glycoprotein may bind polyunsaturated fatty acids. It can cause the extensive fat losses associated with some advanced.

References

Tada T. et al., 1991, J Histochem Cytochem. 39 (9): 1221-6.
Vanni H. et al., 2009, Chest. 135 (5): 1197-208.
Ueyama H. et al., 1991, Biochem Biophys Res Commun. 177 (2): 696-703.