USH1C / Harmonin Antikörper (Antigen Affinität reinigt)

09.03.2012

Produkt-Information von USH1C / Harmonin Antikörper

Immunogen	Recombinant Human USH1C / Harmonin protein (Catalog#10613-H07E)
Antibody Type	Rabbit Polyclonal Antibody ( Antibody Purification Platform )
Ig Type	Rabbit IgG
Formulation	0.2 μm filtered solution in PBS with 5% trehalose
Preparation	Produced in rabbits immunized with purified, recombinant Human USH1C / Harmonin (rh USH1C / Harmonin; Catalog#10613-H07E; Q9Y6N9-1; Met 1-Phe 552). USH1C / Harmonin specific IgG was purified by Human USH1C / Harmonin affinity chromatography.

USH1C / Harmonin Antikörper Usage Guide

Specificity	Human USH1C / Harmonin
Western blot	This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human USH1C in WB. Using a DAB detection system, the detection limit for Human USH1C is approximately 0.5 ng/lane under non-reducing conditions and reducing conditions.
Direct ELISA	This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human USH1C. The detection limit for Human USH1C is approximately 0.00975 ng/well.
Storage	This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Verwandte Produkte & Themen von USH1C / Harmonin Antikörper

Verwandte Produkte:

Proteine:

Antikörper:

Hintergrund von USH1C / Harmonin Antikörper

Harmonin, also known as Antigen NY-CO-38 / NY-CO-37, Autoimmune enteropathy-related antigen AIE-75, Protein PDZ-73, Renal carcinoma antigen NY-REN-3, Usher syndrome type-1C protein and USH1C, is a protein which is expressed in small intestine, colon, kidney, eye and weakly in pancreas. USH1C is expressed also in vestibule of the inner ear. USH1C contains 3PDZ (DHR) domains. USH1C may be involved in protein-protein interaction. Defects in USH1C are the cause of Usher syndrome type 1C (USH1C), also known as Usher syndrome type I Acadian variety. USH is a genetically heterogeneous condition characterized by the association of retinitis pigmentosa and sensorineural deafness. Age at onset and differences in auditory and vestibular function distinguish Usher syndrome type 1 (USH1), Usher syndrome type 2 (USp) and Usher syndrome type 3 (USH3). Defects in USH1C are also the cause of deafness autosomal recessive type 18 (DFNB18) which is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.

References

Verpy, E. et al., 2000, Nat Genet. 26 (1): 51-5.
Weil D., et al., 2003, Hum. Mol. Genet. 12: 463-471.
Reiners,J. et al., 2005, Hum Mol Genet. 14 (24): 3933-43.
Yan,D.et al., 2006,Mol Biol. 357 (3): 755-64.

Sino Biological Inc. liefert USH1C / Harmonin Antikörper (Antigen Affinität reinigt) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

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