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THSD1 Antikörper

Produkt-Information von THSD1 Antikörper

Immunogen

Recombinant Mouse THSD1 protein (Catalog#50400-M08H)

Antibody Type Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform )

Clone ID 

122

Ig Type

Rabbit IgG

Formulation 0.2 μm filtered solution in PBS with 5% trehalose
Preparation

This antibody was obtained from a rabbit immunized with purified, recombinant Mouse THSD1 (rM THSD1; Catalog#50400-M08H; NP_062522.1; Met 1-Asn 412).

Usage Guide von THSD1 Antikörper

Specificity

Mouse THSD1

Western blot This antibody can be used at 1-2 μg/mL with the appropriate secondary reagents to detect Mouse THSD1 in WB. Using a DAB detection system, the detection limit for Mouse THSD1 is approximately 0.25 ng/lane under non-reducing conditions.
Direct ELISA This antibody can be used at 1 μg/mL with the appropriate secondary reagents to detect Mouse THSD1.
Storage This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃.Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Verwandte Produkte & Themen von THSD1 Antikörper

Related Areas:
Proteins:
Antibodies:

Hintergrund von THSD1 Antikörper

Thrombospondin type-1 domain-containing protein 1, also known as transmembrane molecule with thrombospondin module, THSD1 and TMTSP, is a single-pass type I membrane protein which contains oneTSP type-1 domain. Isoform 3 of THSD1 is a secreted protein. THSD1 is a good novel candidate TSG mapping to 13q14. Quantitative reverse transcription-PCR detected down-regulation of THSD1 expression in 100% of ESCC and other cancer cell lines. Mechanisms for THSD1 silencing in ESCC involved loss of heterozygosity and promoter hypermethylation, as analyzed by methylation-specific PCR and clonal bisulfite sequencing. Transfection of wild-type THSD1 into SLMT-1 resulted in significant reduction of colony-forming ability, hence providing functional evidence for its growth-suppressive activity.

References

  1. Kis, E.et al., 2006,Int J Radiat Oncol Biol Phys. 66 (5): 1506-14.
  2. Ko,J.M. et al., 2008,Mol Cancer Res. 6 (4): 592-603.

Sino Biological Inc. liefert THSD1 Antikörper mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über THSD1 Antikörper lesen Sie bitte: http://www.sinobiological.com/THSD1-Antibody-g-9052.html

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