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| Immunogen | Recombinant Mouse Thrombopoietin / THPO protein (Catalog#50146-M08H) |
| Antibody Type | Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform ) |
| Clone ID | 444 |
| Ig Type | Rabbit IgG |
| Formulation | 0.2 μm filtered solution in PBS with 5% trehalose |
| Preparation | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Thrombopoietin / THPO (rM Thrombopoietin / THPO; Catalog#50146-M08H; NP_033405.1; Met 1-Thr 356). |
| Specificity | Mouse Thrombopoietin / THPO |
| Western blot | This antibody can be used at 1-2 μg/mL with the appropriate secondary reagents to detect Mouse THPO in WB. |
| Direct ELISA | This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Mouse THPO. The detection limit for Mouse THPO is approximately 0. 039ng/well. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. |
Thrombopoietin (THPO) is a hematopoietic growth factor that is involved in the regulation of platelet production. This cytokine is composed of an amino-terminal erythropoietin-like domain which is the functional domain and a highly glycosylated carboxyl domain that appears to stabilize circulating thrombopoietin. THPO stimulates both proliferation of progenitor megakaryocytes and their maturation to platelet-producing megakaryocytes, and also accelerates the recovery of platelets. It has been identified that surface c-MPL, the receptor for THPO, binds to the ligand and mediates the action. THPO has multilineage effects in hematopoiesis, not only stimulating megakaryocytopoiesis but also acting in synergy with other cytokines to enhance proliferation and survival of committed erythroid progenitors and primitive hematopoietic stem cells. Mouse THPO is found mainly in the liver, kidney and skeletal muscle.
Sino Biological Inc. liefert Thrombopoietin / THPO Antikörper mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.
Weitere Informationen über Thrombopoietin / THPO Antikörper lesen Sie bitte: http://www.sinobiological.com/Thrombopoietin-THPO-Antibody-g-9206.html
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