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Tetranectin / CLEC3B Antikörper

Produkt-Information von Tetranectin / CLEC3B Antikörper

Immunogen

Recombinant Human Tetranectin / CLEC3B protein (Catalog#12735-H08H)

Antibody Type Mouse Monoclonal Antibody ( Mouse mAb Service Platform )

Clone ID

05

Ig Type

Mouse IgG2a

Formulation 0.2 μm filtered solution in PBS with 5% trehalose
Preparation

This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Tetranectin / CLEC3B (rh Tetranectin / CLEC3B; Catalog#12735-H08H; AAX37102.1; Met 1-Val 202). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.

Usage Guide von Tetranectin / CLEC3B Antikörper

Specificity

Human Tetranectin / CLEC3B

 

No cross-reactivity in ELISA with

Human cell lysate (293 cell line)

Western blot This antibody can be used at 1-2 μg/mL with the appropriate secondary reagents to detect Human CLEC3B in WB.
Direct ELISA 6This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect Human CLEC3B. The detection limit for Human CLEC3B is approximately 0.039 ng/well.
Storage This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Verwandte Produkte & Themen von Tetranectin / CLEC3B Antikörper

Related Areas:

Immunology>>Adhesion Molecule>>Lectin>>Tetranectin/CLEC3B

Proteins:
Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
Tetranectin/CLEC3B Human Tetranectin/CLEC3B Protein, Recombinant 12735-H08H
Tetranectin/CLEC3B Mouse Tetranectin/CLEC3B Protein, Recombinant 50700-M08H
Antibodies:
Molecule Application Description //For Detailed Info. and Price------CLICK! Cat. No
Human Tetranectin/CLEC3B WB, ELISA Tetranectin / CLEC3B Antibody 12735-MM05
Human Tetranectin/CLEC3B WB, ELISA Tetranectin / CLEC3B Antibody (Antigen Affinity Purified) 12735-RP02

Hintergrund von Tetranectin / CLEC3B Antikörper

Tetranectin, also known as C-type lectin domain family 3, member B (CLEC3B), is a homotrimeric plasma and extracellular-matrix protein that binds plasminogen and complex sulphated polysaccharides including heparin. In terms of primary and tertiary structure, Tetranectin is related to the collectin family of Ca (2+)-binding C-type lectins. Tetranectin is encoded in three exons. Exon 3 encodes the carbohydrate recognition domain, which binds to kringle 4 in plasminogen at low levels of Ca (2+). Exon 2 encodes an alpha-helix, which is necessary and sufficient to govern the trimerization of Tetranectin by assembling into a triple-helical coiled-coil structural element. Tetranectin has been suggested to play a role in tissue remodeling, due to its ability to stimulate plasminogen activation and its expression in developing tissues such as developing bone and muscle. Tetranectin enhances plasminogen activation by a tissue-type plasminogen activator so that it has been suggested to play a role in tissue remodeling. TN may play a role in neurological diseases and may serve as a diagnostic aid in multiple sclerosis (MS). The serum or saliva Tetranectin may serve as a potential biomarker for metastatic oral squamous cell carcinoma (OSCC). Decreased plasma Tetranectin or increased Tetranectin in stroma of cancers correlates with cancer progression and adverse prognosis.

References

  1. Lorentsen RH, et al., 2000, Biochem J. 347 Pt 1: 83-7.
  2. Iba K, et al., 2001, Mol Cell Biol. 21 (22): 7817-25.
  3. Iba K, et al., 2009, Wound Repair Regen. 17 (1): 108-12.
  4. Stoevring B, et al., 2006, Scand J Clin Lab Invest. 66 (7): 577-83.
  5. Arellano-Garcia ME, et al., 2010, Int J Mol Sci. 11 (9): 3106-21.
  6. Mogues T, et al., 2004, J Biomed Biotechnol. 2004 (2): 73-8.

Sino Biological Inc. liefert Tetranectin / CLEC3B Antikörper mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über Tetranectin / CLEC3B Antikörper lesen Sie bitte: http://www.sinobiological.com/Tetranectin-CLEC3B-Antibody-g-9500.html

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